New-onset Type 1 Diabetes Mellitus with Diabetic Ketoacidosis and Pancreatitis in a Patient with COVID-19
Coronavirus Disease 2019 (COVID-19) had struck the world with health and economic catastrophes and recently with unusual autoimmune presentations, including new-onset Type 1 Diabetes.Herein we present a 17-year-old male patient who presented to the outptient clinic with fever, palpitation, and cough...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-09-01
|
| Series: | Scientific African |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468227621002192 |
| _version_ | 1819152200780218368 |
|---|---|
| author | Mostafa Alfishawy Mahmoud Nassar Mahmoud Mohamed Moataz Fatthy Riem M. Elmessiery |
| author_facet | Mostafa Alfishawy Mahmoud Nassar Mahmoud Mohamed Moataz Fatthy Riem M. Elmessiery |
| author_sort | Mostafa Alfishawy |
| collection | DOAJ |
| description | Coronavirus Disease 2019 (COVID-19) had struck the world with health and economic catastrophes and recently with unusual autoimmune presentations, including new-onset Type 1 Diabetes.Herein we present a 17-year-old male patient who presented to the outptient clinic with fever, palpitation, and cough of four-week duration; he was referred to the emergency room and was found to have DKA. CT of the chest showed ground-glass opacities suggestive of COVID-19 pneumonia, and abdominal cuts showed dilated intrahepatic biliary radicles with pancreatic loculations suggestive of pancreatitis. The patient was admitted to the ICU, started on intravenous fluids and insulin infusion then COVID-19 PCR returned positive. We hypothesize that SARS-CoV-2 has a vital role in eliciting an autoimmune response triggering type 1 diabetes, and further studies are needed to confirm this hypothesis. SARS-CoV-2 may cause pancreatitis, and the first presentation could be high blood sugar or DKA. |
| first_indexed | 2024-12-22T14:45:31Z |
| format | Article |
| id | doaj.art-ec917941e9714d7385fb6e4007d27a61 |
| institution | Directory Open Access Journal |
| issn | 2468-2276 |
| language | English |
| last_indexed | 2024-12-22T14:45:31Z |
| publishDate | 2021-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Scientific African |
| spelling | doaj.art-ec917941e9714d7385fb6e4007d27a612022-12-21T18:22:28ZengElsevierScientific African2468-22762021-09-0113e00915New-onset Type 1 Diabetes Mellitus with Diabetic Ketoacidosis and Pancreatitis in a Patient with COVID-19Mostafa Alfishawy0Mahmoud Nassar1Mahmoud Mohamed2Moataz Fatthy3Riem M. Elmessiery4Infectious diseases, Infectious Diseases Consultants and Academic Researchers of Egypt (IDCARE), Cairo, EgyptInternal Medicine, Icahn School of Medicine at Mount Sinai / NYC Health + Hospitals / Queens, 82-68 164th St., Queens, New York, 11432, USA; Corresponding author.Medicine department, North Mississippi Medical Center, Tupelo, MS, USAInternal medicine, Faculty of medicine, Cairo university, Cairo, EgyptInternal medicine, Faculty of medicine, Cairo university, Cairo, EgyptCoronavirus Disease 2019 (COVID-19) had struck the world with health and economic catastrophes and recently with unusual autoimmune presentations, including new-onset Type 1 Diabetes.Herein we present a 17-year-old male patient who presented to the outptient clinic with fever, palpitation, and cough of four-week duration; he was referred to the emergency room and was found to have DKA. CT of the chest showed ground-glass opacities suggestive of COVID-19 pneumonia, and abdominal cuts showed dilated intrahepatic biliary radicles with pancreatic loculations suggestive of pancreatitis. The patient was admitted to the ICU, started on intravenous fluids and insulin infusion then COVID-19 PCR returned positive. We hypothesize that SARS-CoV-2 has a vital role in eliciting an autoimmune response triggering type 1 diabetes, and further studies are needed to confirm this hypothesis. SARS-CoV-2 may cause pancreatitis, and the first presentation could be high blood sugar or DKA.http://www.sciencedirect.com/science/article/pii/S2468227621002192New-onsetType 1 diabetes mellitusDiabetic ketoacidosisPancreatitisCOVID-19DKA |
| spellingShingle | Mostafa Alfishawy Mahmoud Nassar Mahmoud Mohamed Moataz Fatthy Riem M. Elmessiery New-onset Type 1 Diabetes Mellitus with Diabetic Ketoacidosis and Pancreatitis in a Patient with COVID-19 Scientific African New-onset Type 1 diabetes mellitus Diabetic ketoacidosis Pancreatitis COVID-19 DKA |
| title | New-onset Type 1 Diabetes Mellitus with Diabetic Ketoacidosis and Pancreatitis in a Patient with COVID-19 |
| title_full | New-onset Type 1 Diabetes Mellitus with Diabetic Ketoacidosis and Pancreatitis in a Patient with COVID-19 |
| title_fullStr | New-onset Type 1 Diabetes Mellitus with Diabetic Ketoacidosis and Pancreatitis in a Patient with COVID-19 |
| title_full_unstemmed | New-onset Type 1 Diabetes Mellitus with Diabetic Ketoacidosis and Pancreatitis in a Patient with COVID-19 |
| title_short | New-onset Type 1 Diabetes Mellitus with Diabetic Ketoacidosis and Pancreatitis in a Patient with COVID-19 |
| title_sort | new onset type 1 diabetes mellitus with diabetic ketoacidosis and pancreatitis in a patient with covid 19 |
| topic | New-onset Type 1 diabetes mellitus Diabetic ketoacidosis Pancreatitis COVID-19 DKA |
| url | http://www.sciencedirect.com/science/article/pii/S2468227621002192 |
| work_keys_str_mv | AT mostafaalfishawy newonsettype1diabetesmellituswithdiabeticketoacidosisandpancreatitisinapatientwithcovid19 AT mahmoudnassar newonsettype1diabetesmellituswithdiabeticketoacidosisandpancreatitisinapatientwithcovid19 AT mahmoudmohamed newonsettype1diabetesmellituswithdiabeticketoacidosisandpancreatitisinapatientwithcovid19 AT moatazfatthy newonsettype1diabetesmellituswithdiabeticketoacidosisandpancreatitisinapatientwithcovid19 AT riemmelmessiery newonsettype1diabetesmellituswithdiabeticketoacidosisandpancreatitisinapatientwithcovid19 |