Maternal septicemia caused by Streptococcus mitis: a possible link between intra-amniotic infection and periodontitis. Case report and literature review
Abstract Background Intra-amniotic infection has a strong causal association with spontaneous preterm birth and preterm prelabor rupture of membranes (PPROM). The most common route of intra-amniotic infection is the ascending pathway in which microorganisms from the vagina gain access to the amnioti...
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| Format: | Article |
| Language: | English |
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BMC
2022-06-01
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| Series: | BMC Infectious Diseases |
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| Online Access: | https://doi.org/10.1186/s12879-022-07530-z |
| _version_ | 1811333857546338304 |
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| author | Piya Chaemsaithong Waranyu Lertrut Threebhorn Kamlungkuea Pitak Santanirand Arunee Singsaneh Adithep Jaovisidha Sasikarn Pakdeeto Paninee Mongkolsuk Pisut Pongchaikul |
| author_facet | Piya Chaemsaithong Waranyu Lertrut Threebhorn Kamlungkuea Pitak Santanirand Arunee Singsaneh Adithep Jaovisidha Sasikarn Pakdeeto Paninee Mongkolsuk Pisut Pongchaikul |
| author_sort | Piya Chaemsaithong |
| collection | DOAJ |
| description | Abstract Background Intra-amniotic infection has a strong causal association with spontaneous preterm birth and preterm prelabor rupture of membranes (PPROM). The most common route of intra-amniotic infection is the ascending pathway in which microorganisms from the vagina gain access to the amniotic cavity. Distant microorganisms such as those from the oral cavity have been reported in intra-amniotic infection through hematogenous spreading. Case presentation A 31-year-old gravida 1, para 0 Thai woman at 33+6 weeks’ gestation presented with leakage of vaginal fluid and irregular uterine contraction. She developed fever at 4 h after admission and was later diagnosed with acute chorioamnionitis. A Cesarean section was performed to terminate pregnancy. In addition to a blood culture, the cultures of amniotic fluid, vaginal and chorioamniotic membrane swabs were positive for Streptococcus mitis with identical susceptibility profiles. After the delivery and antibiotic prescription, oral examination showed dental caries and chronic periodontitis. Conclusions This is the first case report demonstrating maternal septicemia and intra-amniotic infection caused by S. mitis which might be attributed to periodontitis in women presenting with preterm PROM. We highlighted the association of periodontal disease and preterm labor/PROM syndrome. Oral cavity examination should be included in the prenatal care to ensure good dental hygiene. |
| first_indexed | 2024-04-13T16:59:06Z |
| format | Article |
| id | doaj.art-ec93105b3e2647d6a83b0c9877878c79 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-04-13T16:59:06Z |
| publishDate | 2022-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-ec93105b3e2647d6a83b0c9877878c792022-12-22T02:38:44ZengBMCBMC Infectious Diseases1471-23342022-06-012211910.1186/s12879-022-07530-zMaternal septicemia caused by Streptococcus mitis: a possible link between intra-amniotic infection and periodontitis. Case report and literature reviewPiya Chaemsaithong0Waranyu Lertrut1Threebhorn Kamlungkuea2Pitak Santanirand3Arunee Singsaneh4Adithep Jaovisidha5Sasikarn Pakdeeto6Paninee Mongkolsuk7Pisut Pongchaikul8Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityDepartment of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityDepartment of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityDepartment of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityDepartment of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityDepartment of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityChakri Naruebodindra Medical Institute, Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityChakri Naruebodindra Medical Institute, Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityChakri Naruebodindra Medical Institute, Faculty of Medicine, Ramathibodi Hospital, Mahidol UniversityAbstract Background Intra-amniotic infection has a strong causal association with spontaneous preterm birth and preterm prelabor rupture of membranes (PPROM). The most common route of intra-amniotic infection is the ascending pathway in which microorganisms from the vagina gain access to the amniotic cavity. Distant microorganisms such as those from the oral cavity have been reported in intra-amniotic infection through hematogenous spreading. Case presentation A 31-year-old gravida 1, para 0 Thai woman at 33+6 weeks’ gestation presented with leakage of vaginal fluid and irregular uterine contraction. She developed fever at 4 h after admission and was later diagnosed with acute chorioamnionitis. A Cesarean section was performed to terminate pregnancy. In addition to a blood culture, the cultures of amniotic fluid, vaginal and chorioamniotic membrane swabs were positive for Streptococcus mitis with identical susceptibility profiles. After the delivery and antibiotic prescription, oral examination showed dental caries and chronic periodontitis. Conclusions This is the first case report demonstrating maternal septicemia and intra-amniotic infection caused by S. mitis which might be attributed to periodontitis in women presenting with preterm PROM. We highlighted the association of periodontal disease and preterm labor/PROM syndrome. Oral cavity examination should be included in the prenatal care to ensure good dental hygiene.https://doi.org/10.1186/s12879-022-07530-zChorioamnionitisDental cariesIntra-amniotic infectionMicrobial invasion of amniotic cavityPeriodontal diseasePeriodontitis |
| spellingShingle | Piya Chaemsaithong Waranyu Lertrut Threebhorn Kamlungkuea Pitak Santanirand Arunee Singsaneh Adithep Jaovisidha Sasikarn Pakdeeto Paninee Mongkolsuk Pisut Pongchaikul Maternal septicemia caused by Streptococcus mitis: a possible link between intra-amniotic infection and periodontitis. Case report and literature review BMC Infectious Diseases Chorioamnionitis Dental caries Intra-amniotic infection Microbial invasion of amniotic cavity Periodontal disease Periodontitis |
| title | Maternal septicemia caused by Streptococcus mitis: a possible link between intra-amniotic infection and periodontitis. Case report and literature review |
| title_full | Maternal septicemia caused by Streptococcus mitis: a possible link between intra-amniotic infection and periodontitis. Case report and literature review |
| title_fullStr | Maternal septicemia caused by Streptococcus mitis: a possible link between intra-amniotic infection and periodontitis. Case report and literature review |
| title_full_unstemmed | Maternal septicemia caused by Streptococcus mitis: a possible link between intra-amniotic infection and periodontitis. Case report and literature review |
| title_short | Maternal septicemia caused by Streptococcus mitis: a possible link between intra-amniotic infection and periodontitis. Case report and literature review |
| title_sort | maternal septicemia caused by streptococcus mitis a possible link between intra amniotic infection and periodontitis case report and literature review |
| topic | Chorioamnionitis Dental caries Intra-amniotic infection Microbial invasion of amniotic cavity Periodontal disease Periodontitis |
| url | https://doi.org/10.1186/s12879-022-07530-z |
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