Cell Creeping and Controlled Migration by Magnetic Carbon Nanotubes
<p>Abstract</p> <p>Carbon nanotubes (CNTs) are tubular nanostructures that exhibit magnetic properties due to the metal catalyst impurities entrapped at their extremities during fabrication. When mammalian cells are cultured in a CNT-containing medium, the nanotubes interact with t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2009-01-01
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| Series: | Nanoscale Research Letters |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1007/s11671-009-9463-y |
| _version_ | 1797716896431210496 |
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| author | Ciofani G Pensabene V Raffa V Vittorio O Cuschieri A |
| author_facet | Ciofani G Pensabene V Raffa V Vittorio O Cuschieri A |
| author_sort | Ciofani G |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Carbon nanotubes (CNTs) are tubular nanostructures that exhibit magnetic properties due to the metal catalyst impurities entrapped at their extremities during fabrication. When mammalian cells are cultured in a CNT-containing medium, the nanotubes interact with the cells, as a result of which, on exposure to a magnetic field, they are able to move cells towards the magnetic source. In the present paper, we report on a model that describes the dynamics of this mammalian cell movement in a magnetic field consequent on CNT attachment. The model is based on Bell’s theory of unbinding dynamics of receptor-ligand bonds modified and validated by experimental data of the movement dynamics of mammalian cells cultured with nanotubes and exposed to a magnetic field, generated by a permanent magnet, in the vicinity of the cell culture wells. We demonstrate that when the applied magnetic force is below a critical value (about <it>F</it> <sub>c</sub> ≈ 10<sup>−11</sup> N), the cell ‘creeps’ very slowly on the culture dish at a very low velocity (10–20 nm/s) but becomes detached from the substrate when this critical magnetic force is exceeded and then move towards the magnetic source.</p> |
| first_indexed | 2024-03-12T08:29:18Z |
| format | Article |
| id | doaj.art-ec9467528c514c20b55ec9a7647bb8e8 |
| institution | Directory Open Access Journal |
| issn | 1931-7573 1556-276X |
| language | English |
| last_indexed | 2024-03-12T08:29:18Z |
| publishDate | 2009-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Nanoscale Research Letters |
| spelling | doaj.art-ec9467528c514c20b55ec9a7647bb8e82023-09-02T17:57:25ZengSpringerOpenNanoscale Research Letters1931-75731556-276X2009-01-0151257262Cell Creeping and Controlled Migration by Magnetic Carbon NanotubesCiofani GPensabene VRaffa VVittorio OCuschieri A<p>Abstract</p> <p>Carbon nanotubes (CNTs) are tubular nanostructures that exhibit magnetic properties due to the metal catalyst impurities entrapped at their extremities during fabrication. When mammalian cells are cultured in a CNT-containing medium, the nanotubes interact with the cells, as a result of which, on exposure to a magnetic field, they are able to move cells towards the magnetic source. In the present paper, we report on a model that describes the dynamics of this mammalian cell movement in a magnetic field consequent on CNT attachment. The model is based on Bell’s theory of unbinding dynamics of receptor-ligand bonds modified and validated by experimental data of the movement dynamics of mammalian cells cultured with nanotubes and exposed to a magnetic field, generated by a permanent magnet, in the vicinity of the cell culture wells. We demonstrate that when the applied magnetic force is below a critical value (about <it>F</it> <sub>c</sub> ≈ 10<sup>−11</sup> N), the cell ‘creeps’ very slowly on the culture dish at a very low velocity (10–20 nm/s) but becomes detached from the substrate when this critical magnetic force is exceeded and then move towards the magnetic source.</p>http://dx.doi.org/10.1007/s11671-009-9463-yCell creeping and migrationCarbon nanotubesMagnetism |
| spellingShingle | Ciofani G Pensabene V Raffa V Vittorio O Cuschieri A Cell Creeping and Controlled Migration by Magnetic Carbon Nanotubes Nanoscale Research Letters Cell creeping and migration Carbon nanotubes Magnetism |
| title | Cell Creeping and Controlled Migration by Magnetic Carbon Nanotubes |
| title_full | Cell Creeping and Controlled Migration by Magnetic Carbon Nanotubes |
| title_fullStr | Cell Creeping and Controlled Migration by Magnetic Carbon Nanotubes |
| title_full_unstemmed | Cell Creeping and Controlled Migration by Magnetic Carbon Nanotubes |
| title_short | Cell Creeping and Controlled Migration by Magnetic Carbon Nanotubes |
| title_sort | cell creeping and controlled migration by magnetic carbon nanotubes |
| topic | Cell creeping and migration Carbon nanotubes Magnetism |
| url | http://dx.doi.org/10.1007/s11671-009-9463-y |
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