Multiplex genome engineering in Clostridium beijerinckii NCIMB 8052 using CRISPR-Cas12a

Multiplex genome engineering in Clostridium beijerinckii NCIMB 8052 using CRISPR-Cas12a

Abstract Clostridium species are re-emerging as biotechnological workhorses for industrial acetone–butanol–ethanol production. This re-emergence is largely due to advances in fermentation technologies but also due to advances in genome engineering and re-programming of the native metabolism. Several...

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Bibliographic Details
Main Authors: Constantinos Patinios, Stijn T. de Vries, Mamou Diallo, Lucrezia Lanza, Pepijn L. J. V. Q. Verbrugge, Ana M. López-Contreras, John van der Oost, Ruud A. Weusthuis, Servé W. M. Kengen
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-37220-y

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