Radiological and Functional Pulmonary Evolution in Post-COVID-19 Patients: An Observational Study
COVID-19 has generated a scenario for global health with multiple systemic impairments. This retrospective study evaluated the clinical, radiological, and pulmonary functional evolution in 302 post-COVID-19 patients. Regarding post-COVID-19 pulmonary symptoms, dry cough, dyspnea, and chest pain were...
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MDPI AG
2023-08-01
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| Series: | Diseases |
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| Online Access: | https://www.mdpi.com/2079-9721/11/3/113 |
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| author | Virgínia Maria Cavallari Strozze Catharin Tereza Laís Menegucci Zutin Elen Landgraf Guiguer Adriano Cressoni Araújo Lucas Fornari Laurindo Eduardo F. Baisi Chagas Cássia Fernanda Gasparotti Zorzetto Patrícia C. dos Santos Bueno Manoela dos Santos Bueno Yandra Cervelim Nunes Vitor Cavallari Strozze Catharin Heron Fernando Gonzaga Sandra Maria Barbalho |
| author_facet | Virgínia Maria Cavallari Strozze Catharin Tereza Laís Menegucci Zutin Elen Landgraf Guiguer Adriano Cressoni Araújo Lucas Fornari Laurindo Eduardo F. Baisi Chagas Cássia Fernanda Gasparotti Zorzetto Patrícia C. dos Santos Bueno Manoela dos Santos Bueno Yandra Cervelim Nunes Vitor Cavallari Strozze Catharin Heron Fernando Gonzaga Sandra Maria Barbalho |
| author_sort | Virgínia Maria Cavallari Strozze Catharin |
| collection | DOAJ |
| description | COVID-19 has generated a scenario for global health with multiple systemic impairments. This retrospective study evaluated the clinical, radiological, and pulmonary functional evolution in 302 post-COVID-19 patients. Regarding post-COVID-19 pulmonary symptoms, dry cough, dyspnea, and chest pain were the most frequent. Of the associated comorbidities, asthma was more frequent (23.5%). Chest tomography (CT) initially showed a mean pulmonary involvement of 69.7%, and evaluation in the subsequent months showed improvement in the evolutionary image. With less than six months post-pathology, there was a commitment of 37.7% from six to twelve months it was 20%, and after 12 months it was 9.9%. As for most of the sample, 50.3% of the patients presented CT normalization less than six months after infection, 23% were normalized between six and twelve months, and 5.2% presented with normalized images after twelve months, with one remaining. A percentage of 17.3% maintained post-COVID-19 pulmonary residual sequelae. Regarding spirometry, less than six months after pathology, 59.3% of the patients presented regular exam results, 12.3% had their function normalized within six to twelve months, and 6.3% had normal exam results twelve months after their post-pathology evaluation. Only 3.6% of the patients still showed some alteration during this period. |
| first_indexed | 2024-03-10T22:52:45Z |
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| id | doaj.art-ec9b45ab75214eee911fb7f478a5fa88 |
| institution | Directory Open Access Journal |
| issn | 2079-9721 |
| language | English |
| last_indexed | 2024-03-10T22:52:45Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diseases |
| spelling | doaj.art-ec9b45ab75214eee911fb7f478a5fa882023-11-19T10:15:27ZengMDPI AGDiseases2079-97212023-08-0111311310.3390/diseases11030113Radiological and Functional Pulmonary Evolution in Post-COVID-19 Patients: An Observational StudyVirgínia Maria Cavallari Strozze Catharin0Tereza Laís Menegucci Zutin1Elen Landgraf Guiguer2Adriano Cressoni Araújo3Lucas Fornari Laurindo4Eduardo F. Baisi Chagas5Cássia Fernanda Gasparotti Zorzetto6Patrícia C. dos Santos Bueno7Manoela dos Santos Bueno8Yandra Cervelim Nunes9Vitor Cavallari Strozze Catharin10Heron Fernando Gonzaga11Sandra Maria Barbalho12Department of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Avenida Hygino Muzzy Filho, 1001, Marília 17525-902, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Avenida Hygino Muzzy Filho, 1001, Marília 17525-902, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Avenida Hygino Muzzy Filho, 1001, Marília 17525-902, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Avenida Hygino Muzzy Filho, 1001, Marília 17525-902, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Avenida Hygino Muzzy Filho, 1001, Marília 17525-902, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Avenida Hygino Muzzy Filho, 1001, Marília 17525-902, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Avenida Hygino Muzzy Filho, 1001, Marília 17525-902, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Avenida Hygino Muzzy Filho, 1001, Marília 17525-902, São Paulo, BrazilUNIMED Marilia-R. Bororós, 225-Sen. Salgado Filho, Marília 17502-270, São Paulo, BrazilDepartment of Biochemistry and Nutrition, School of Food and Technology of Marília (FATEC), Avenida Castro Alves, 62, Marília 17500-000, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Avenida Hygino Muzzy Filho, 1001, Marília 17525-902, São Paulo, BrazilDepartment of Dermatology, Escola Paulista de Medicina, Federal University of São Paulo (UNIFESP), Rua dos Otonis, 861, São Paulo 04025-002, São Paulo, BrazilDepartment of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR), Avenida Hygino Muzzy Filho, 1001, Marília 17525-902, São Paulo, BrazilCOVID-19 has generated a scenario for global health with multiple systemic impairments. This retrospective study evaluated the clinical, radiological, and pulmonary functional evolution in 302 post-COVID-19 patients. Regarding post-COVID-19 pulmonary symptoms, dry cough, dyspnea, and chest pain were the most frequent. Of the associated comorbidities, asthma was more frequent (23.5%). Chest tomography (CT) initially showed a mean pulmonary involvement of 69.7%, and evaluation in the subsequent months showed improvement in the evolutionary image. With less than six months post-pathology, there was a commitment of 37.7% from six to twelve months it was 20%, and after 12 months it was 9.9%. As for most of the sample, 50.3% of the patients presented CT normalization less than six months after infection, 23% were normalized between six and twelve months, and 5.2% presented with normalized images after twelve months, with one remaining. A percentage of 17.3% maintained post-COVID-19 pulmonary residual sequelae. Regarding spirometry, less than six months after pathology, 59.3% of the patients presented regular exam results, 12.3% had their function normalized within six to twelve months, and 6.3% had normal exam results twelve months after their post-pathology evaluation. Only 3.6% of the patients still showed some alteration during this period.https://www.mdpi.com/2079-9721/11/3/113COVID-19post-COVID-19pulmonary manifestationsspirometrychest tomography |
| spellingShingle | Virgínia Maria Cavallari Strozze Catharin Tereza Laís Menegucci Zutin Elen Landgraf Guiguer Adriano Cressoni Araújo Lucas Fornari Laurindo Eduardo F. Baisi Chagas Cássia Fernanda Gasparotti Zorzetto Patrícia C. dos Santos Bueno Manoela dos Santos Bueno Yandra Cervelim Nunes Vitor Cavallari Strozze Catharin Heron Fernando Gonzaga Sandra Maria Barbalho Radiological and Functional Pulmonary Evolution in Post-COVID-19 Patients: An Observational Study Diseases COVID-19 post-COVID-19 pulmonary manifestations spirometry chest tomography |
| title | Radiological and Functional Pulmonary Evolution in Post-COVID-19 Patients: An Observational Study |
| title_full | Radiological and Functional Pulmonary Evolution in Post-COVID-19 Patients: An Observational Study |
| title_fullStr | Radiological and Functional Pulmonary Evolution in Post-COVID-19 Patients: An Observational Study |
| title_full_unstemmed | Radiological and Functional Pulmonary Evolution in Post-COVID-19 Patients: An Observational Study |
| title_short | Radiological and Functional Pulmonary Evolution in Post-COVID-19 Patients: An Observational Study |
| title_sort | radiological and functional pulmonary evolution in post covid 19 patients an observational study |
| topic | COVID-19 post-COVID-19 pulmonary manifestations spirometry chest tomography |
| url | https://www.mdpi.com/2079-9721/11/3/113 |
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