Potential Factors Associated with Pelvic Lymph Node Metastasis in Endometrioid Endometrial Carcinoma

Objectives: To explore factors that associated with pelvic lymph node metastasis in endometrioid endometrial carcinomaMaterials and Methods: Two hundred and ninety-three patients with endometrioid endometrial carcinoma, who received surgical staging in Siriraj Hospital during 2008-2016,...

Full description

Bibliographic Details
Main Authors: Prakasit Karavanich, Atthapon Jaishuen
Format: Article
Language:English
Published: The Royal Thai College of Obstetricians and Gynaecologists 2020-04-01
Series:Thai Journal of Obstetrics and Gynaecology
Subjects:
Online Access:https://he02.tci-thaijo.org/index.php/tjog/article/download/148354/163938/
Description
Summary:Objectives: To explore factors that associated with pelvic lymph node metastasis in endometrioid endometrial carcinomaMaterials and Methods: Two hundred and ninety-three patients with endometrioid endometrial carcinoma, who received surgical staging in Siriraj Hospital during 2008-2016, were studied. The relationship between pelvic lymph node metastasis and these data: demographic factors, biochemical markers, preoperative and intraoperative tumor characteristics were analysed by using a logistic regression model. Results: From multivariate analysis, associated factors were grade of tumor, platelet count, deep myometrial invasion (deep MI: more than half of myometrial invasion) and size of tumor. Platelet count and size of tumor were re-calculated. Thrombocytosis (platelet count more than or equal to 380,000/mm3) and large tumor (tumor size more than or equal to 6 centimeters) were statistically significant for cut-off point. Conclusion: Grade of tumor, platelet count, more than half of depth of myometrial invasion and size of tumor, were associated with pelvic lymph node metastasis in endometrioid endometrial carcinoma.
ISSN:0857-6084