Human Monkeypox Outbreak Caused by Novel Virus Belonging to Congo Basin Clade, Sudan, 2005
To determine the outbreak source of monkeypox virus (MPXV) infections in Unity State, Sudan, in November 2005, we conducted a retrospective investigation. MPXV was identified in a sub-Sahelian savannah environment. Three case notification categories were used: suspected, probable, and confirmed. Mol...
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2010-10-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/16/10/10-0713_article |
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| author | Pierre Formenty Mohammed O. Muntasir Inger K. Damon Vipul Chowdhary Martin L. Opoka Charlotte Monimart Elmangory M. Mutasim Jean-Claude Manuguerra Whitni B. Davidson Kevin L. Karem Jeanne Cabeza Sharlenna Wang Mamunur R. Malik Thierry Durand Abdalhalim Khalid Thomas Rioton Andrea Kuong-Ruay Alimagboul A. Babiker Mubarak E.M. Karsani Magdi S. Abdalla |
| author_facet | Pierre Formenty Mohammed O. Muntasir Inger K. Damon Vipul Chowdhary Martin L. Opoka Charlotte Monimart Elmangory M. Mutasim Jean-Claude Manuguerra Whitni B. Davidson Kevin L. Karem Jeanne Cabeza Sharlenna Wang Mamunur R. Malik Thierry Durand Abdalhalim Khalid Thomas Rioton Andrea Kuong-Ruay Alimagboul A. Babiker Mubarak E.M. Karsani Magdi S. Abdalla |
| author_sort | Pierre Formenty |
| collection | DOAJ |
| description | To determine the outbreak source of monkeypox virus (MPXV) infections in Unity State, Sudan, in November 2005, we conducted a retrospective investigation. MPXV was identified in a sub-Sahelian savannah environment. Three case notification categories were used: suspected, probable, and confirmed. Molecular, virologic, and serologic assays were used to test blood specimens, vesicular swabs, and crust specimens obtained from symptomatic and recovering persons. Ten laboratory-confirmed cases and 9 probable cases of MPXV were reported during September–December 2005; no deaths occurred. Human-to-human transmission up to 5 generations was described. Our investigation could not fully determine the source of the outbreak. Preliminary data indicate that the MPXV strain isolated during this outbreak was a novel virus belonging to the Congo Basin clade. Our results indicate that MPXV should be considered endemic to the wetland areas of Unity State. This finding will enhance understanding of the ecologic niche for this virus. |
| first_indexed | 2024-12-11T22:33:17Z |
| format | Article |
| id | doaj.art-ec9f57c3d37e477f879bc3a585b78e99 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-11T22:33:17Z |
| publishDate | 2010-10-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-ec9f57c3d37e477f879bc3a585b78e992022-12-22T00:48:04ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592010-10-0116101539154510.3201/eid1610.100713Human Monkeypox Outbreak Caused by Novel Virus Belonging to Congo Basin Clade, Sudan, 2005Pierre FormentyMohammed O. MuntasirInger K. DamonVipul ChowdharyMartin L. OpokaCharlotte MonimartElmangory M. MutasimJean-Claude ManuguerraWhitni B. DavidsonKevin L. KaremJeanne CabezaSharlenna WangMamunur R. MalikThierry DurandAbdalhalim KhalidThomas RiotonAndrea Kuong-RuayAlimagboul A. BabikerMubarak E.M. KarsaniMagdi S. AbdallaTo determine the outbreak source of monkeypox virus (MPXV) infections in Unity State, Sudan, in November 2005, we conducted a retrospective investigation. MPXV was identified in a sub-Sahelian savannah environment. Three case notification categories were used: suspected, probable, and confirmed. Molecular, virologic, and serologic assays were used to test blood specimens, vesicular swabs, and crust specimens obtained from symptomatic and recovering persons. Ten laboratory-confirmed cases and 9 probable cases of MPXV were reported during September–December 2005; no deaths occurred. Human-to-human transmission up to 5 generations was described. Our investigation could not fully determine the source of the outbreak. Preliminary data indicate that the MPXV strain isolated during this outbreak was a novel virus belonging to the Congo Basin clade. Our results indicate that MPXV should be considered endemic to the wetland areas of Unity State. This finding will enhance understanding of the ecologic niche for this virus.https://wwwnc.cdc.gov/eid/article/16/10/10-0713_articleMonkeypoxorthopoxvirusepidemiologyoutbreakzoonosisviruses |
| spellingShingle | Pierre Formenty Mohammed O. Muntasir Inger K. Damon Vipul Chowdhary Martin L. Opoka Charlotte Monimart Elmangory M. Mutasim Jean-Claude Manuguerra Whitni B. Davidson Kevin L. Karem Jeanne Cabeza Sharlenna Wang Mamunur R. Malik Thierry Durand Abdalhalim Khalid Thomas Rioton Andrea Kuong-Ruay Alimagboul A. Babiker Mubarak E.M. Karsani Magdi S. Abdalla Human Monkeypox Outbreak Caused by Novel Virus Belonging to Congo Basin Clade, Sudan, 2005 Emerging Infectious Diseases Monkeypox orthopoxvirus epidemiology outbreak zoonosis viruses |
| title | Human Monkeypox Outbreak Caused by Novel Virus Belonging to Congo Basin Clade, Sudan, 2005 |
| title_full | Human Monkeypox Outbreak Caused by Novel Virus Belonging to Congo Basin Clade, Sudan, 2005 |
| title_fullStr | Human Monkeypox Outbreak Caused by Novel Virus Belonging to Congo Basin Clade, Sudan, 2005 |
| title_full_unstemmed | Human Monkeypox Outbreak Caused by Novel Virus Belonging to Congo Basin Clade, Sudan, 2005 |
| title_short | Human Monkeypox Outbreak Caused by Novel Virus Belonging to Congo Basin Clade, Sudan, 2005 |
| title_sort | human monkeypox outbreak caused by novel virus belonging to congo basin clade sudan 2005 |
| topic | Monkeypox orthopoxvirus epidemiology outbreak zoonosis viruses |
| url | https://wwwnc.cdc.gov/eid/article/16/10/10-0713_article |
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