Clinical applications of retrograde autologous priming in cardiopulmonary bypass in pediatric cardiac surgery
Retrograde autologous priming (RAP) has been routinely applied in cardiac pediatric cardiopulmonary bypass (CPB). However, this technique is performed in pediatric patients weighing more than 20 kg, and research about its application in pediatric patients weighing less than 20 kg is still scarce. Th...
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Divulgação Científica
2016-01-01
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| Series: | Brazilian Journal of Medical and Biological Research |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000500703&lng=en&tlng=en |
| _version_ | 1817976934300123136 |
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| author | G.W. Fu Y.F. Nie Z.Y. Jiao W.Z. Zhao |
| author_facet | G.W. Fu Y.F. Nie Z.Y. Jiao W.Z. Zhao |
| author_sort | G.W. Fu |
| collection | DOAJ |
| description | Retrograde autologous priming (RAP) has been routinely applied in cardiac pediatric cardiopulmonary bypass (CPB). However, this technique is performed in pediatric patients weighing more than 20 kg, and research about its application in pediatric patients weighing less than 20 kg is still scarce. This study explored the clinical application of RAP in CPB in pediatric patients undergoing cardiac surgery. Sixty pediatric patients scheduled for cardiac surgery were randomly divided into control and experimental groups. The experimental group was treated with CPB using RAP, while the control group was treated with conventional CPB (priming with suspended red blood cells, plasma and albumin). The hematocrit (Hct) and lactate (Lac) levels at different perioperative time-points, mechanical ventilation time, hospitalization duration, and intraoperative and postoperative blood usage were recorded. Results showed that Hct levels at 15 min after CPB beginning (T2) and at CPB end (T3), and number of intraoperative blood transfusions were significantly lower in the experimental group (P<0.05). There were no significant differences in CPB time, aortic blocking time, T2-Lac value or T3-Lac between the two groups (P>0.05). Postoperatively, there were no significant differences in Hct (2 h after surgery), mechanical ventilation time, intensive care unit time, or postoperative blood transfusion between two groups (P>0.05). RAP can effectively reduce the hemodilution when using less or not using any banked blood, while meeting the intraoperative perfusion conditions, and decreasing the perioperative blood transfusion volume in pediatric patients. |
| first_indexed | 2024-04-13T22:10:30Z |
| format | Article |
| id | doaj.art-eca1daee31a644d887fccc663b55a1ce |
| institution | Directory Open Access Journal |
| issn | 1414-431X |
| language | English |
| last_indexed | 2024-04-13T22:10:30Z |
| publishDate | 2016-01-01 |
| publisher | Associação Brasileira de Divulgação Científica |
| record_format | Article |
| series | Brazilian Journal of Medical and Biological Research |
| spelling | doaj.art-eca1daee31a644d887fccc663b55a1ce2022-12-22T02:27:47ZengAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research1414-431X2016-01-0149510.1590/1414-431X20165138S0100-879X2016000500703Clinical applications of retrograde autologous priming in cardiopulmonary bypass in pediatric cardiac surgeryG.W. FuY.F. NieZ.Y. JiaoW.Z. ZhaoRetrograde autologous priming (RAP) has been routinely applied in cardiac pediatric cardiopulmonary bypass (CPB). However, this technique is performed in pediatric patients weighing more than 20 kg, and research about its application in pediatric patients weighing less than 20 kg is still scarce. This study explored the clinical application of RAP in CPB in pediatric patients undergoing cardiac surgery. Sixty pediatric patients scheduled for cardiac surgery were randomly divided into control and experimental groups. The experimental group was treated with CPB using RAP, while the control group was treated with conventional CPB (priming with suspended red blood cells, plasma and albumin). The hematocrit (Hct) and lactate (Lac) levels at different perioperative time-points, mechanical ventilation time, hospitalization duration, and intraoperative and postoperative blood usage were recorded. Results showed that Hct levels at 15 min after CPB beginning (T2) and at CPB end (T3), and number of intraoperative blood transfusions were significantly lower in the experimental group (P<0.05). There were no significant differences in CPB time, aortic blocking time, T2-Lac value or T3-Lac between the two groups (P>0.05). Postoperatively, there were no significant differences in Hct (2 h after surgery), mechanical ventilation time, intensive care unit time, or postoperative blood transfusion between two groups (P>0.05). RAP can effectively reduce the hemodilution when using less or not using any banked blood, while meeting the intraoperative perfusion conditions, and decreasing the perioperative blood transfusion volume in pediatric patients.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000500703&lng=en&tlng=enCardiopulmonary bypassRetrograde autologous primingCardiac surgery |
| spellingShingle | G.W. Fu Y.F. Nie Z.Y. Jiao W.Z. Zhao Clinical applications of retrograde autologous priming in cardiopulmonary bypass in pediatric cardiac surgery Brazilian Journal of Medical and Biological Research Cardiopulmonary bypass Retrograde autologous priming Cardiac surgery |
| title | Clinical applications of retrograde autologous priming in cardiopulmonary bypass in pediatric cardiac surgery |
| title_full | Clinical applications of retrograde autologous priming in cardiopulmonary bypass in pediatric cardiac surgery |
| title_fullStr | Clinical applications of retrograde autologous priming in cardiopulmonary bypass in pediatric cardiac surgery |
| title_full_unstemmed | Clinical applications of retrograde autologous priming in cardiopulmonary bypass in pediatric cardiac surgery |
| title_short | Clinical applications of retrograde autologous priming in cardiopulmonary bypass in pediatric cardiac surgery |
| title_sort | clinical applications of retrograde autologous priming in cardiopulmonary bypass in pediatric cardiac surgery |
| topic | Cardiopulmonary bypass Retrograde autologous priming Cardiac surgery |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000500703&lng=en&tlng=en |
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