Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation

Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation

Excessive use of hard-to-degrade pesticides threatens the ecological health of aquatic systems. This study aimed to investigate difenoconazole (DFZ) residues in the environment induced neurotoxicity in carp and the underlying mechanisms. A total of thirty-six carps were divided into three groups and...

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Bibliographic Details
Main Authors: Feixue Liu, Yan Wang, Li Chen, Babatunde Kazeem Bello, Tianmeng Zhang, Haitao Yang, Xueqing Li, Enzhuang Pan, Huimiao Feng, Jingquan Dong
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Difenoconazole
Blood-brain barrier
Neurotoxicity
Nrf2
ROS
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322009216

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http://www.sciencedirect.com/science/article/pii/S0147651322009216

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