Short-term associations of low-level fine particulate matter (PM2.5) with cardiorespiratory hospitalizations in 139 Japanese cities
There have been few studies in non-western countries on the relationship between low levels of daily fine particulate matter (PM2.5) exposure and morbidity or mortality, and the impact of PM2.5 concentrations below 15 μg/m3, which is the latest World Health Organization Air Quality Guideline (WHO AQ...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | Ecotoxicology and Environmental Safety |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651323004657 |
| _version_ | 1797823389786701824 |
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| author | Kohei Hasegawa Teruomi Tsukahara Tetsuo Nomiyama |
| author_facet | Kohei Hasegawa Teruomi Tsukahara Tetsuo Nomiyama |
| author_sort | Kohei Hasegawa |
| collection | DOAJ |
| description | There have been few studies in non-western countries on the relationship between low levels of daily fine particulate matter (PM2.5) exposure and morbidity or mortality, and the impact of PM2.5 concentrations below 15 μg/m3, which is the latest World Health Organization Air Quality Guideline (WHO AQG) value for the 24-h mean, is not yet clear. We assessed the associations between low-level PM2.5 exposure and cardiorespiratory admissions in Japan. We collected the daily hospital admission count data, air pollutant data, and meteorological condition data recorded from April 2016 to March 2019 in 139 Japanese cities. City-specific estimates were obtained from conditional logistic regression models in a time-stratified case-crossover design and pooled by random-effect models. We estimated that every 10-μg/m3 increase in the concurrent-day PM2.5 concentration was related to a 0.52% increase in cardiovascular admissions (95% CI: 0.13–0.92%) and a 1.74% increase in respiratory admissions (95% CI: 1.41–2.07%). These values were nearly the same when the datasets were filtered to contain only daily PM2.5 concentrations <15 μg/m3. The exposure–response curves showed approximately sublinear-to-linear curves with no indication of thresholds. These associations with cardiovascular diseases weakened after adjusting for nitrogen dioxide or sulfur dioxide, but associations with respiratory diseases were almost unchanged when additionally adjusted for other pollutants. This study demonstrated that associations between daily PM2.5 and daily cardiorespiratory hospitalizations might persist at low concentrations, including those below the latest WHO AQG value. Our findings suggest that the updated guideline value may still be insufficient from the perspective of public health. |
| first_indexed | 2024-03-13T10:23:18Z |
| format | Article |
| id | doaj.art-eca8787a64e74de5b4a105165869eea7 |
| institution | Directory Open Access Journal |
| issn | 0147-6513 |
| language | English |
| last_indexed | 2024-03-13T10:23:18Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ecotoxicology and Environmental Safety |
| spelling | doaj.art-eca8787a64e74de5b4a105165869eea72023-05-20T04:29:01ZengElsevierEcotoxicology and Environmental Safety0147-65132023-06-01258114961Short-term associations of low-level fine particulate matter (PM2.5) with cardiorespiratory hospitalizations in 139 Japanese citiesKohei Hasegawa0Teruomi Tsukahara1Tetsuo Nomiyama2Department of Preventive Medicine and Public Health, School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan; Corresponding author.Department of Preventive Medicine and Public Health, School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan; Department of Occupational Medicine, School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, JapanDepartment of Preventive Medicine and Public Health, School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan; Department of Occupational Medicine, School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, JapanThere have been few studies in non-western countries on the relationship between low levels of daily fine particulate matter (PM2.5) exposure and morbidity or mortality, and the impact of PM2.5 concentrations below 15 μg/m3, which is the latest World Health Organization Air Quality Guideline (WHO AQG) value for the 24-h mean, is not yet clear. We assessed the associations between low-level PM2.5 exposure and cardiorespiratory admissions in Japan. We collected the daily hospital admission count data, air pollutant data, and meteorological condition data recorded from April 2016 to March 2019 in 139 Japanese cities. City-specific estimates were obtained from conditional logistic regression models in a time-stratified case-crossover design and pooled by random-effect models. We estimated that every 10-μg/m3 increase in the concurrent-day PM2.5 concentration was related to a 0.52% increase in cardiovascular admissions (95% CI: 0.13–0.92%) and a 1.74% increase in respiratory admissions (95% CI: 1.41–2.07%). These values were nearly the same when the datasets were filtered to contain only daily PM2.5 concentrations <15 μg/m3. The exposure–response curves showed approximately sublinear-to-linear curves with no indication of thresholds. These associations with cardiovascular diseases weakened after adjusting for nitrogen dioxide or sulfur dioxide, but associations with respiratory diseases were almost unchanged when additionally adjusted for other pollutants. This study demonstrated that associations between daily PM2.5 and daily cardiorespiratory hospitalizations might persist at low concentrations, including those below the latest WHO AQG value. Our findings suggest that the updated guideline value may still be insufficient from the perspective of public health.http://www.sciencedirect.com/science/article/pii/S0147651323004657Air pollutionLow concentrationFine particulate matterHospital admission |
| spellingShingle | Kohei Hasegawa Teruomi Tsukahara Tetsuo Nomiyama Short-term associations of low-level fine particulate matter (PM2.5) with cardiorespiratory hospitalizations in 139 Japanese cities Ecotoxicology and Environmental Safety Air pollution Low concentration Fine particulate matter Hospital admission |
| title | Short-term associations of low-level fine particulate matter (PM2.5) with cardiorespiratory hospitalizations in 139 Japanese cities |
| title_full | Short-term associations of low-level fine particulate matter (PM2.5) with cardiorespiratory hospitalizations in 139 Japanese cities |
| title_fullStr | Short-term associations of low-level fine particulate matter (PM2.5) with cardiorespiratory hospitalizations in 139 Japanese cities |
| title_full_unstemmed | Short-term associations of low-level fine particulate matter (PM2.5) with cardiorespiratory hospitalizations in 139 Japanese cities |
| title_short | Short-term associations of low-level fine particulate matter (PM2.5) with cardiorespiratory hospitalizations in 139 Japanese cities |
| title_sort | short term associations of low level fine particulate matter pm2 5 with cardiorespiratory hospitalizations in 139 japanese cities |
| topic | Air pollution Low concentration Fine particulate matter Hospital admission |
| url | http://www.sciencedirect.com/science/article/pii/S0147651323004657 |
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