Infliximab Therapeutic monitoring by tryptic peptide LC-MS/MS method improvements lead to improved accuracy with decreased imprecision and turnaround time

Introduction: Therapeutic drug monitoring of infliximab has become the standard of care for inflammatory bowel disease in the setting of loss of response to therapy, and occasionally in proactive therapy personalization. Measurement of infliximab by tryptic peptide HPLC-MS/MS has been available sinc...

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Bibliographic Details
Main Authors: Paula M. Ladwig, Ann L. Rivard, Alex Barbeln, Anthony Maus, David L. Murray, Melissa R. Snyder, Maria A.V. Willrich
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Journal of Mass Spectrometry and Advances in the Clinical Lab
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667145X24000075