The clinical evaluation of Vi-one chlorhexidine mouthwash on plaque-induced gingivitis: A double-blind randomized clinical trial
Background: Chlorhexidine (CHX) is the most effective antiseptic mouthwash to date. Essential oil such as thymol, have inhibitory and biocidal effects a range of bacteria. Objective: To determine the effect of mouthwash containing CHX and thymol on plaque induced gingivitis. Methods: This double-...
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| Format: | Article |
| Language: | English |
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Electronic Physician
2017-09-01
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| Series: | Electronic Physician |
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633216/ |
| _version_ | 1818525803641569280 |
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| author | Babak Amoian Marzyeh Omidbakhsh Soraya Khafri |
| author_facet | Babak Amoian Marzyeh Omidbakhsh Soraya Khafri |
| author_sort | Babak Amoian |
| collection | DOAJ |
| description | Background: Chlorhexidine (CHX) is the most effective antiseptic mouthwash to date. Essential oil such as
thymol, have inhibitory and biocidal effects a range of bacteria.
Objective: To determine the effect of mouthwash containing CHX and thymol on plaque induced gingivitis.
Methods: This double-blind randomized clinical trial study was performed on 60 patients with plaque induced
gingivitis who were randomly divided into two groups: Group I (CHX/thymol mouthwash-Vi-one) and Group II
(CHX mouthwash-Behsa). Patients in each group underwent scaling and root planning and polishing, then were
educated about BASS-Method brushing, and were recommended Oral-B toothbrushes and Pooneh toothpaste.
The two groups were asked to rinse their mouths for 60 seconds twice a day, once in the morning and once at
night, after brushing their teeth. Plaque index, gingival index, bleeding index and stain index were evaluated at
baseline and 14 days later in Ramfjord teeth. Data analysis was conducted using SPSS version 21. Independent- samples t-test and paired-samples t-test were used for data analysis.
Results: The results showed that plaque index and gingival index significantly reduced in two groups (p<0.001).
However, group I was significantly more efficient than group II (p<0.001, p=0.021 respectively). Similar results
were observed in terms of bleeding index with the difference that the two groups did not differ significantly from
each other (p=0.879). Both groups significantly increased the stain index. No remarkable difference was also
observed between the two groups (p=0.754).
Conclusion: Based on the results of this study, we can conclude that the CHX/thymol mouthwash can be offered
to patients with dental plaque-induced gingivitis, because it appears to be more effective in controlling dental
plaque and gingivitis.
Trial registration: The trial was registered at the Iranian Registry of Clinical Trials (http://www.irct.ir) with the
Irct ID: IRCT201602231760N45.
Funding: This study was part of a thesis and research project (Grant No: 9440921) supported and funded by
Babol University of Medical Sciences. The authors received no financial support from Behsa pharmaceutical
company (Behsa mouthwash manufacturer) or Rojin cosmetic laboratory (Vi-one mouthwash manufacturer) for
this study |
| first_indexed | 2024-12-11T06:14:10Z |
| format | Article |
| id | doaj.art-ecad23ab233d44a08aa8deeff88b2983 |
| institution | Directory Open Access Journal |
| issn | 2008-5842 2008-5842 |
| language | English |
| last_indexed | 2024-12-11T06:14:10Z |
| publishDate | 2017-09-01 |
| publisher | Electronic Physician |
| record_format | Article |
| series | Electronic Physician |
| spelling | doaj.art-ecad23ab233d44a08aa8deeff88b29832022-12-22T01:18:02ZengElectronic PhysicianElectronic Physician2008-58422008-58422017-09-01995223522810.19082/5223The clinical evaluation of Vi-one chlorhexidine mouthwash on plaque-induced gingivitis: A double-blind randomized clinical trialBabak AmoianMarzyeh OmidbakhshSoraya KhafriBackground: Chlorhexidine (CHX) is the most effective antiseptic mouthwash to date. Essential oil such as thymol, have inhibitory and biocidal effects a range of bacteria. Objective: To determine the effect of mouthwash containing CHX and thymol on plaque induced gingivitis. Methods: This double-blind randomized clinical trial study was performed on 60 patients with plaque induced gingivitis who were randomly divided into two groups: Group I (CHX/thymol mouthwash-Vi-one) and Group II (CHX mouthwash-Behsa). Patients in each group underwent scaling and root planning and polishing, then were educated about BASS-Method brushing, and were recommended Oral-B toothbrushes and Pooneh toothpaste. The two groups were asked to rinse their mouths for 60 seconds twice a day, once in the morning and once at night, after brushing their teeth. Plaque index, gingival index, bleeding index and stain index were evaluated at baseline and 14 days later in Ramfjord teeth. Data analysis was conducted using SPSS version 21. Independent- samples t-test and paired-samples t-test were used for data analysis. Results: The results showed that plaque index and gingival index significantly reduced in two groups (p<0.001). However, group I was significantly more efficient than group II (p<0.001, p=0.021 respectively). Similar results were observed in terms of bleeding index with the difference that the two groups did not differ significantly from each other (p=0.879). Both groups significantly increased the stain index. No remarkable difference was also observed between the two groups (p=0.754). Conclusion: Based on the results of this study, we can conclude that the CHX/thymol mouthwash can be offered to patients with dental plaque-induced gingivitis, because it appears to be more effective in controlling dental plaque and gingivitis. Trial registration: The trial was registered at the Iranian Registry of Clinical Trials (http://www.irct.ir) with the Irct ID: IRCT201602231760N45. Funding: This study was part of a thesis and research project (Grant No: 9440921) supported and funded by Babol University of Medical Sciences. The authors received no financial support from Behsa pharmaceutical company (Behsa mouthwash manufacturer) or Rojin cosmetic laboratory (Vi-one mouthwash manufacturer) for this studyhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633216/MouthwashesChlorhexidineGingivitisPeriodontal index |
| spellingShingle | Babak Amoian Marzyeh Omidbakhsh Soraya Khafri The clinical evaluation of Vi-one chlorhexidine mouthwash on plaque-induced gingivitis: A double-blind randomized clinical trial Electronic Physician Mouthwashes Chlorhexidine Gingivitis Periodontal index |
| title | The clinical evaluation of Vi-one chlorhexidine mouthwash on plaque-induced gingivitis: A double-blind randomized clinical trial |
| title_full | The clinical evaluation of Vi-one chlorhexidine mouthwash on plaque-induced gingivitis: A double-blind randomized clinical trial |
| title_fullStr | The clinical evaluation of Vi-one chlorhexidine mouthwash on plaque-induced gingivitis: A double-blind randomized clinical trial |
| title_full_unstemmed | The clinical evaluation of Vi-one chlorhexidine mouthwash on plaque-induced gingivitis: A double-blind randomized clinical trial |
| title_short | The clinical evaluation of Vi-one chlorhexidine mouthwash on plaque-induced gingivitis: A double-blind randomized clinical trial |
| title_sort | clinical evaluation of vi one chlorhexidine mouthwash on plaque induced gingivitis a double blind randomized clinical trial |
| topic | Mouthwashes Chlorhexidine Gingivitis Periodontal index |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633216/ |
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