MiR-21, MiR-29a, GATA4, and MEF2c Expression Changes in Endothelin-1 and Angiotensin II Cardiac Hypertrophy Stimulated Isl-1<sup>+</sup>Sca-1<sup>+</sup>c-kit<sup>+</sup> Porcine Cardiac Progenitor Cells In Vitro

MiR-21, MiR-29a, GATA4, and MEF2c Expression Changes in Endothelin-1 and Angiotensin II Cardiac Hypertrophy Stimulated Isl-1<sup>+</sup>Sca-1<sup>+</sup>c-kit<sup>+</sup> Porcine Cardiac Progenitor Cells In Vitro

Cost- and time-intensive porcine translational disease models offer great opportunities to test drugs and therapies for pathological cardiac hypertrophy and can be supported by porcine cell culture models that provide further insights into basic disease mechanisms. Cardiac progenitor cells (CPCs) re...

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Bibliographic Details
Main Authors: Katrin Zlabinger, Andreas Spannbauer, Denise Traxler, Alfred Gugerell, Dominika Lukovic, Johannes Winkler, Julia Mester-Tonczar, Bruno Podesser, Mariann Gyöngyösi
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cells
Subjects:
porcine cardiac progenitor cells
cardiac hypertrophy
cardiac remodeling
isl-1
angiotensin ii
endothelin 1
mef2c
gata4
mir-21
mir29a
Online Access:https://www.mdpi.com/2073-4409/8/11/1416

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