Long term intrinsic cycling in human life course antibody responses to influenza A(H3N2): an observational and modeling study

Long term intrinsic cycling in human life course antibody responses to influenza A(H3N2): an observational and modeling study

Background: Over a life course, human adaptive immunity to antigenically mutable pathogens exhibits competitive and facilitative interactions. We hypothesize that such interactions may lead to cyclic dynamics in immune responses over a lifetime. Methods: To investigate the cyclic behavior, we analyz...

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Bibliographic Details
Main Authors: Bingyi Yang, Bernardo García-Carreras, Justin Lessler, Jonathan M Read, Huachen Zhu, C Jessica E Metcalf, James A Hay, Kin O Kwok, Ruiyun Shen, Chao Q Jiang, Yi Guan, Steven Riley, Derek A Cummings
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-12-01
Series:eLife
Subjects:
influenza
antibody
dynamics
Online Access:https://elifesciences.org/articles/81457

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