Choroidal Vascularity Map in Unilateral Central Serous Chorioretinopathy: A Comparison with Fellow and Healthy Eyes
Background: To map the choroidal vascularity index and compare two eyes in patients with unilateral central serous chorioretinopathy (CSCR). Methods: This was a retrospective, observational study performed in patients with unilateral CSCR. Choroidal thickness (CT) and Choroidal vascularity index (CV...
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MDPI AG
2021-05-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/5/861 |
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| author | Niroj Kumar Sahoo Sumit Randhir Singh Oliver Beale Gideon Nkrumah Mohammed Abdul Rasheed Asiya Jabeen Kiran Kumar Vupparaboina Mohammed Nasar Ibrahim Filippo Tatti Khushboo Chandra Michele Lanza Claudio Iovino Enrico Peiretti Jay Chhablani |
| author_facet | Niroj Kumar Sahoo Sumit Randhir Singh Oliver Beale Gideon Nkrumah Mohammed Abdul Rasheed Asiya Jabeen Kiran Kumar Vupparaboina Mohammed Nasar Ibrahim Filippo Tatti Khushboo Chandra Michele Lanza Claudio Iovino Enrico Peiretti Jay Chhablani |
| author_sort | Niroj Kumar Sahoo |
| collection | DOAJ |
| description | Background: To map the choroidal vascularity index and compare two eyes in patients with unilateral central serous chorioretinopathy (CSCR). Methods: This was a retrospective, observational study performed in patients with unilateral CSCR. Choroidal thickness (CT) and Choroidal vascularity index (CVI) were measured and mapped in various zones according to the early treatment diabetic retinopathy (ETDRS) grid. Results: A total of 20 CSCR patients (20 study and 20 fellow eyes) were included in the study. Outer nasal region CT was seen to be significantly lower than central CT (<i>p</i> = 0.042) and inner nasal CT (<i>p</i> = 0.007); outer ring CT was significantly less than central (<i>p</i> = 0.04) and inner ring (<i>p</i> = 0.01) CT in CSCR eyes. On potting all the CVI values against the corresponding CT values, a positive correlation was seen in CSCR eyes (<i>r</i> = 0.54, <i>p</i> < 0.01), which was slightly weaker in fellow eyes (<i>r</i> = 0.3, <i>p</i> < 0.01) and a negative correlation was seen in healthy eyes (<i>r</i> = −0.262, <i>p</i> < 0.01). Conclusions: Correlation between CVI and CT was altered in CSCR eyes as compared to fellow and normal eyes with increasing CVI towards the center of the macula and superiorly in CSCR eyes. |
| first_indexed | 2024-03-10T11:33:13Z |
| format | Article |
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| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T11:33:13Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-ecb42cc2e49c46869660474fc559ec4b2023-11-21T19:08:10ZengMDPI AGDiagnostics2075-44182021-05-0111586110.3390/diagnostics11050861Choroidal Vascularity Map in Unilateral Central Serous Chorioretinopathy: A Comparison with Fellow and Healthy EyesNiroj Kumar Sahoo0Sumit Randhir Singh1Oliver Beale2Gideon Nkrumah3Mohammed Abdul Rasheed4Asiya Jabeen5Kiran Kumar Vupparaboina6Mohammed Nasar Ibrahim7Filippo Tatti8Khushboo Chandra9Michele Lanza10Claudio Iovino11Enrico Peiretti12Jay Chhablani13Department of Retina and Vitreous, L V Prasad Eye Institute, Vijayawada 521134, IndiaJacobs Retina Center, Shiley Eye Institute, University of California San Diego, San Diego, CA 92697, USAUPMC Eye Centre, University of Pittsburgh, Pittsburgh, PA 15213, USAUPMC Eye Centre, University of Pittsburgh, Pittsburgh, PA 15213, USASchool of Optometry and Vision Science, University of Waterloo, Waterloo, ON N2L 3G1, CanadaSchool of Optometry and Vision Science, University of Waterloo, Waterloo, ON N2L 3G1, CanadaUPMC Eye Centre, University of Pittsburgh, Pittsburgh, PA 15213, USADepartment of Electrical Engineering, Indian Institute of Technology, Hyderabad 502285, IndiaDepartment of Surgical Sciences, Eye Clinic, University of Cagliari, 9121 Cagliari, ItalyDepartment of Vitreoretina, Disha Eye Hospitals Pvt Ltd., 88(63A) Ghosh Para Road, Barrackpore, Kolkata 700120, IndiaEye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania Luigi Vanvitelli, 81100 Naples, ItalyEye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania Luigi Vanvitelli, 81100 Naples, ItalyDepartment of Surgical Sciences, Eye Clinic, University of Cagliari, 9121 Cagliari, ItalyUPMC Eye Centre, University of Pittsburgh, Pittsburgh, PA 15213, USABackground: To map the choroidal vascularity index and compare two eyes in patients with unilateral central serous chorioretinopathy (CSCR). Methods: This was a retrospective, observational study performed in patients with unilateral CSCR. Choroidal thickness (CT) and Choroidal vascularity index (CVI) were measured and mapped in various zones according to the early treatment diabetic retinopathy (ETDRS) grid. Results: A total of 20 CSCR patients (20 study and 20 fellow eyes) were included in the study. Outer nasal region CT was seen to be significantly lower than central CT (<i>p</i> = 0.042) and inner nasal CT (<i>p</i> = 0.007); outer ring CT was significantly less than central (<i>p</i> = 0.04) and inner ring (<i>p</i> = 0.01) CT in CSCR eyes. On potting all the CVI values against the corresponding CT values, a positive correlation was seen in CSCR eyes (<i>r</i> = 0.54, <i>p</i> < 0.01), which was slightly weaker in fellow eyes (<i>r</i> = 0.3, <i>p</i> < 0.01) and a negative correlation was seen in healthy eyes (<i>r</i> = −0.262, <i>p</i> < 0.01). Conclusions: Correlation between CVI and CT was altered in CSCR eyes as compared to fellow and normal eyes with increasing CVI towards the center of the macula and superiorly in CSCR eyes.https://www.mdpi.com/2075-4418/11/5/861central serous chorioretinopathyCSCRchoroidal vascularity indexCVImappingETDRS grid |
| spellingShingle | Niroj Kumar Sahoo Sumit Randhir Singh Oliver Beale Gideon Nkrumah Mohammed Abdul Rasheed Asiya Jabeen Kiran Kumar Vupparaboina Mohammed Nasar Ibrahim Filippo Tatti Khushboo Chandra Michele Lanza Claudio Iovino Enrico Peiretti Jay Chhablani Choroidal Vascularity Map in Unilateral Central Serous Chorioretinopathy: A Comparison with Fellow and Healthy Eyes Diagnostics central serous chorioretinopathy CSCR choroidal vascularity index CVI mapping ETDRS grid |
| title | Choroidal Vascularity Map in Unilateral Central Serous Chorioretinopathy: A Comparison with Fellow and Healthy Eyes |
| title_full | Choroidal Vascularity Map in Unilateral Central Serous Chorioretinopathy: A Comparison with Fellow and Healthy Eyes |
| title_fullStr | Choroidal Vascularity Map in Unilateral Central Serous Chorioretinopathy: A Comparison with Fellow and Healthy Eyes |
| title_full_unstemmed | Choroidal Vascularity Map in Unilateral Central Serous Chorioretinopathy: A Comparison with Fellow and Healthy Eyes |
| title_short | Choroidal Vascularity Map in Unilateral Central Serous Chorioretinopathy: A Comparison with Fellow and Healthy Eyes |
| title_sort | choroidal vascularity map in unilateral central serous chorioretinopathy a comparison with fellow and healthy eyes |
| topic | central serous chorioretinopathy CSCR choroidal vascularity index CVI mapping ETDRS grid |
| url | https://www.mdpi.com/2075-4418/11/5/861 |
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