Determinanet of the survival pattern of tuberculosis patients treated under directly observed treatment short course at Pawe Hospital, Ethiopia

Abstract: Tuberculosis (TB) is still a public health problem and amongst the top 10 leading causes of death. The objective of this study is to analyze the survival time of TB patients and identify the risk factors that influence their survival in Pawe Hospital during the treatment period. The data f...

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Main Authors: Tsehay Haile, Kasim Mohammed, Endeshaw Assefa
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Cogent Medicine
Subjects:
Online Access:http://dx.doi.org/10.1080/2331205X.2021.1944477
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author Tsehay Haile
Kasim Mohammed
Endeshaw Assefa
author_facet Tsehay Haile
Kasim Mohammed
Endeshaw Assefa
author_sort Tsehay Haile
collection DOAJ
description Abstract: Tuberculosis (TB) is still a public health problem and amongst the top 10 leading causes of death. The objective of this study is to analyze the survival time of TB patients and identify the risk factors that influence their survival in Pawe Hospital during the treatment period. The data for this study are obtained from TB patients registered books from September 2009 to January 2010 under Directly Observed Treatment, Short-course (DOTS) at the health centers in Pawe Hospital. The analytical methodologies used were the Kaplan–Meier to estimate the survival time and Cox’s regression model to identify the covariates that have a statistically significant effect on the survival longevity of TB patients. The estimation of the model parameters was done by partial maximum likelihood procedures. The multivariate analysis of the Cox regression model gives that age, category (patient category), initial weight and HIV status have statistically significant effects on the survival longevity of TB patients. On the other hand, sex, marital status, and history of previous treatment have no impact on the survival experience of TB patients. The study shows that 84.5% of the patients were still alive at the end of 8 months of anti-TB treatment. Based on the result of the study, different factors are identified for the death of TB. Patients recommended that TB co-infected people should have awareness about the hazard of the risk factors identified in this study, and health workers should be cautious when a patient has lower Initial weight and HIV-positive status.
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spelling doaj.art-ecbaaea31f544c3281eb59a47f1d85932022-12-22T03:37:58ZengTaylor & Francis GroupCogent Medicine2331-205X2021-01-018110.1080/2331205X.2021.19444771944477Determinanet of the survival pattern of tuberculosis patients treated under directly observed treatment short course at Pawe Hospital, EthiopiaTsehay Haile0Kasim Mohammed1Endeshaw Assefa2Biostatistics, Pawi Hospital, Benshangul GumzUniversity of Gondar, College of Natural and Computational SciencesUniversity of Gondar, College of Natural and Computational SciencesAbstract: Tuberculosis (TB) is still a public health problem and amongst the top 10 leading causes of death. The objective of this study is to analyze the survival time of TB patients and identify the risk factors that influence their survival in Pawe Hospital during the treatment period. The data for this study are obtained from TB patients registered books from September 2009 to January 2010 under Directly Observed Treatment, Short-course (DOTS) at the health centers in Pawe Hospital. The analytical methodologies used were the Kaplan–Meier to estimate the survival time and Cox’s regression model to identify the covariates that have a statistically significant effect on the survival longevity of TB patients. The estimation of the model parameters was done by partial maximum likelihood procedures. The multivariate analysis of the Cox regression model gives that age, category (patient category), initial weight and HIV status have statistically significant effects on the survival longevity of TB patients. On the other hand, sex, marital status, and history of previous treatment have no impact on the survival experience of TB patients. The study shows that 84.5% of the patients were still alive at the end of 8 months of anti-TB treatment. Based on the result of the study, different factors are identified for the death of TB. Patients recommended that TB co-infected people should have awareness about the hazard of the risk factors identified in this study, and health workers should be cautious when a patient has lower Initial weight and HIV-positive status.http://dx.doi.org/10.1080/2331205X.2021.1944477tuberculosisdeathdirectly observed treatment-short courserevised national tuberculosis control program
spellingShingle Tsehay Haile
Kasim Mohammed
Endeshaw Assefa
Determinanet of the survival pattern of tuberculosis patients treated under directly observed treatment short course at Pawe Hospital, Ethiopia
Cogent Medicine
tuberculosis
death
directly observed treatment-short course
revised national tuberculosis control program
title Determinanet of the survival pattern of tuberculosis patients treated under directly observed treatment short course at Pawe Hospital, Ethiopia
title_full Determinanet of the survival pattern of tuberculosis patients treated under directly observed treatment short course at Pawe Hospital, Ethiopia
title_fullStr Determinanet of the survival pattern of tuberculosis patients treated under directly observed treatment short course at Pawe Hospital, Ethiopia
title_full_unstemmed Determinanet of the survival pattern of tuberculosis patients treated under directly observed treatment short course at Pawe Hospital, Ethiopia
title_short Determinanet of the survival pattern of tuberculosis patients treated under directly observed treatment short course at Pawe Hospital, Ethiopia
title_sort determinanet of the survival pattern of tuberculosis patients treated under directly observed treatment short course at pawe hospital ethiopia
topic tuberculosis
death
directly observed treatment-short course
revised national tuberculosis control program
url http://dx.doi.org/10.1080/2331205X.2021.1944477
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AT endeshawassefa determinanetofthesurvivalpatternoftuberculosispatientstreatedunderdirectlyobservedtreatmentshortcourseatpawehospitalethiopia