Identification of Predictive Biomarkers of Response to HSP90 Inhibitors in Lung Adenocarcinoma

Identification of Predictive Biomarkers of Response to HSP90 Inhibitors in Lung Adenocarcinoma

Heat shock protein 90 (HSP90) plays an essential role in lung adenocarcinoma, acting as a key chaperone involved in the correct functioning of numerous highly relevant protein drivers of this disease. To this end, HSP90 inhibitors have emerged as promising therapeutic strategies, even though respons...

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Bibliographic Details
Main Authors: Ángela Marrugal, Irene Ferrer, David Gómez-Sánchez, Álvaro Quintanal-Villalonga, María Dolores Pastor, Laura Ojeda, Luis Paz-Ares, Sonia Molina-Pinelo
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
HSP90 inhibitors
protein biomarkers predictive of response
lung adenocarcinoma
Online Access:https://www.mdpi.com/1422-0067/22/5/2538

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