Impact of different stages of chronic kidney disease on the severity of Willis–Ekbom disease
Introduction: Willis–Ekbom disease (WED)/restless legs syndrome (RLS) is a disorder in which the patient has neurologic features such as urge of rhythmic limb movement that may decrease or stop when the limb is moved. In this study, we had tried to compare the severity of WED in different stages of...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Journal of Family Medicine and Primary Care |
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| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2019;volume=8;issue=2;spage=432;epage=436;aulast=Bhagawati |
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| author | Jahnabi Bhagawati Sunil Kumar Abhijeet Kumar Agrawal Sourya Acharya Anil K Wanjari Tarachand K Kamble |
| author_facet | Jahnabi Bhagawati Sunil Kumar Abhijeet Kumar Agrawal Sourya Acharya Anil K Wanjari Tarachand K Kamble |
| author_sort | Jahnabi Bhagawati |
| collection | DOAJ |
| description | Introduction: Willis–Ekbom disease (WED)/restless legs syndrome (RLS) is a disorder in which the patient has neurologic features such as urge of rhythmic limb movement that may decrease or stop when the limb is moved. In this study, we had tried to compare the severity of WED in different stages of chronic kidney disease (CKD). Materials and Methods: In this study, a total of 300 patients with CKD who were >18 years of age were included. All the participants were subjected to questionnaire for the diagnosis of RLS (essential clinical criteria for the diagnosis of RLS) and a questionnaire on International Restless Legs Syndrome Study Group Rating Scale for its severity. Observation and Results: Our study showed a prevalence of 20% of WED in patients with CKD. Patients with CKD on hemodialysis had significantly more WED than the conservative group (P = 0.0001). Patients with a history of diabetes mellitus showed significant correlation with WED (P = 0.026), while patients who had a history of hypertension showed both diabetes mellitus and hypertension and smoking had no significant relation with WED (P = 0.27, P = 0.23, and P = 0.22, respectively). The different stages of CKD showed significant correlation with WED (P = 0.002), with more WED among patients with stage V CKD. WED was more in patients on hemodialysis (P = 0.0001). The correlation of different stages of CKD with the severity of WED was statistically significant (P = 0.029), with WED being more severe among stage V CKD. Conclusion: WED was more prevalent among patients with CKD who are on maintenance hemodialysis and diabetes mellitus. However, no such relation could be established for hypertension alone. Patients with higher grades of CKD were more prone to have WED symptoms, and the severity of these symptoms increases with the stages of CKD. |
| first_indexed | 2024-04-12T06:41:59Z |
| format | Article |
| id | doaj.art-ecbf8065fc2b4d39a1d915c51ede57b6 |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-04-12T06:41:59Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-ecbf8065fc2b4d39a1d915c51ede57b62022-12-22T03:43:41ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632019-01-018243243610.4103/jfmpc.jfmpc_418_18Impact of different stages of chronic kidney disease on the severity of Willis–Ekbom diseaseJahnabi BhagawatiSunil KumarAbhijeet Kumar AgrawalSourya AcharyaAnil K WanjariTarachand K KambleIntroduction: Willis–Ekbom disease (WED)/restless legs syndrome (RLS) is a disorder in which the patient has neurologic features such as urge of rhythmic limb movement that may decrease or stop when the limb is moved. In this study, we had tried to compare the severity of WED in different stages of chronic kidney disease (CKD). Materials and Methods: In this study, a total of 300 patients with CKD who were >18 years of age were included. All the participants were subjected to questionnaire for the diagnosis of RLS (essential clinical criteria for the diagnosis of RLS) and a questionnaire on International Restless Legs Syndrome Study Group Rating Scale for its severity. Observation and Results: Our study showed a prevalence of 20% of WED in patients with CKD. Patients with CKD on hemodialysis had significantly more WED than the conservative group (P = 0.0001). Patients with a history of diabetes mellitus showed significant correlation with WED (P = 0.026), while patients who had a history of hypertension showed both diabetes mellitus and hypertension and smoking had no significant relation with WED (P = 0.27, P = 0.23, and P = 0.22, respectively). The different stages of CKD showed significant correlation with WED (P = 0.002), with more WED among patients with stage V CKD. WED was more in patients on hemodialysis (P = 0.0001). The correlation of different stages of CKD with the severity of WED was statistically significant (P = 0.029), with WED being more severe among stage V CKD. Conclusion: WED was more prevalent among patients with CKD who are on maintenance hemodialysis and diabetes mellitus. However, no such relation could be established for hypertension alone. Patients with higher grades of CKD were more prone to have WED symptoms, and the severity of these symptoms increases with the stages of CKD.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2019;volume=8;issue=2;spage=432;epage=436;aulast=BhagawatiChronic kidney diseaserestless legs syndromeseverityWillis–Ekbom disease prevalence |
| spellingShingle | Jahnabi Bhagawati Sunil Kumar Abhijeet Kumar Agrawal Sourya Acharya Anil K Wanjari Tarachand K Kamble Impact of different stages of chronic kidney disease on the severity of Willis–Ekbom disease Journal of Family Medicine and Primary Care Chronic kidney disease restless legs syndrome severity Willis–Ekbom disease prevalence |
| title | Impact of different stages of chronic kidney disease on the severity of Willis–Ekbom disease |
| title_full | Impact of different stages of chronic kidney disease on the severity of Willis–Ekbom disease |
| title_fullStr | Impact of different stages of chronic kidney disease on the severity of Willis–Ekbom disease |
| title_full_unstemmed | Impact of different stages of chronic kidney disease on the severity of Willis–Ekbom disease |
| title_short | Impact of different stages of chronic kidney disease on the severity of Willis–Ekbom disease |
| title_sort | impact of different stages of chronic kidney disease on the severity of willis ekbom disease |
| topic | Chronic kidney disease restless legs syndrome severity Willis–Ekbom disease prevalence |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2019;volume=8;issue=2;spage=432;epage=436;aulast=Bhagawati |
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