The effect of surface nucleation modulation on the mechanical and biocompatibility of metal-polymer biomaterials
The deployment of hernia repair patches in laparoscopic procedures is gradually increasing. In this technology, however, understanding the new phases of titanium from the parent phase on polymer substrates is essential to control the microstructural transition and material properties. It remains a c...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-04-01
|
| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1160351/full |
| _version_ | 1797851338594320384 |
|---|---|
| author | Zhenhong Ye Zhenhong Ye Le Zhang Taiwei Liu Weicheng Xuan Xiaodong He Changhao Hou Donglin Han Binbin Yu Junye Shi Jie Kang Jiangping Chen Jiangping Chen |
| author_facet | Zhenhong Ye Zhenhong Ye Le Zhang Taiwei Liu Weicheng Xuan Xiaodong He Changhao Hou Donglin Han Binbin Yu Junye Shi Jie Kang Jiangping Chen Jiangping Chen |
| author_sort | Zhenhong Ye |
| collection | DOAJ |
| description | The deployment of hernia repair patches in laparoscopic procedures is gradually increasing. In this technology, however, understanding the new phases of titanium from the parent phase on polymer substrates is essential to control the microstructural transition and material properties. It remains a challenging area of condensed matter physics to predict the kinetic and thermodynamic properties of metals on polymer substrates from the molecular scale due to the lack of understanding of the properties of the metal-polymer interface. However, this paper revealed the mechanism of nucleation on polymer substrates and proposed for the first record a time-dependent regulatory mechanism for the polymer-titanium interface. The interconnection between polymer surface chain entanglement, nucleation and growth patterns, crystal structure and surface roughness were effectively unified. The secondary regulation of mechanical properties was accomplished simultaneously to satisfy the requirement of biocompatibility. Titaniumized polypropylene patches prepared by time-dependent magnetron sputtering technology demonstrated excellent interfacial mechanical properties and biocompatibility. In addition, modulation by low-temperature plasma metal deposition opened a new pathway for biomaterials. This paper provides a solid theoretical basis for the research of titanium nanofilms on medical polypropylene substrates and the medical industry of implantable biomaterials, which will be of great value in the future. |
| first_indexed | 2024-04-09T19:15:11Z |
| format | Article |
| id | doaj.art-ecc09d6b7c2d46c4a6c119705eb2e795 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-09T19:15:11Z |
| publishDate | 2023-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-ecc09d6b7c2d46c4a6c119705eb2e7952023-04-06T06:17:41ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852023-04-011110.3389/fbioe.2023.11603511160351The effect of surface nucleation modulation on the mechanical and biocompatibility of metal-polymer biomaterialsZhenhong Ye0Zhenhong Ye1Le Zhang2Taiwei Liu3Weicheng Xuan4Xiaodong He5Changhao Hou6Donglin Han7Binbin Yu8Junye Shi9Jie Kang10Jiangping Chen11Jiangping Chen12Institute of Refrigeration and Cryogenics, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaShanghai High Efficiency Cooling System Research Center, Shanghai, ChinaState Key Laboratory for Oncogenes and Bio-ID Center, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Engineering Mechanics, School of Naval Architecture, Ocean and Civil Engineering, Shanghai Jiao Tong University, Shanghai, ChinaInstitute of Refrigeration and Cryogenics, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Engineering Mechanics and Innovation Center for Advanced Ship and Deep-Sea Exploration, School of Naval Architecture, Ocean and Civil Engineering Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Urology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaInstitute of Refrigeration and Cryogenics, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaInstitute of Refrigeration and Cryogenics, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaInstitute of Refrigeration and Cryogenics, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of General Surgery, Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai, ChinaInstitute of Refrigeration and Cryogenics, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, ChinaShanghai High Efficiency Cooling System Research Center, Shanghai, ChinaThe deployment of hernia repair patches in laparoscopic procedures is gradually increasing. In this technology, however, understanding the new phases of titanium from the parent phase on polymer substrates is essential to control the microstructural transition and material properties. It remains a challenging area of condensed matter physics to predict the kinetic and thermodynamic properties of metals on polymer substrates from the molecular scale due to the lack of understanding of the properties of the metal-polymer interface. However, this paper revealed the mechanism of nucleation on polymer substrates and proposed for the first record a time-dependent regulatory mechanism for the polymer-titanium interface. The interconnection between polymer surface chain entanglement, nucleation and growth patterns, crystal structure and surface roughness were effectively unified. The secondary regulation of mechanical properties was accomplished simultaneously to satisfy the requirement of biocompatibility. Titaniumized polypropylene patches prepared by time-dependent magnetron sputtering technology demonstrated excellent interfacial mechanical properties and biocompatibility. In addition, modulation by low-temperature plasma metal deposition opened a new pathway for biomaterials. This paper provides a solid theoretical basis for the research of titanium nanofilms on medical polypropylene substrates and the medical industry of implantable biomaterials, which will be of great value in the future.https://www.frontiersin.org/articles/10.3389/fbioe.2023.1160351/fullnucleation analysisbiomechanicsherniahyperviscoelasticityvalence bond analysis |
| spellingShingle | Zhenhong Ye Zhenhong Ye Le Zhang Taiwei Liu Weicheng Xuan Xiaodong He Changhao Hou Donglin Han Binbin Yu Junye Shi Jie Kang Jiangping Chen Jiangping Chen The effect of surface nucleation modulation on the mechanical and biocompatibility of metal-polymer biomaterials Frontiers in Bioengineering and Biotechnology nucleation analysis biomechanics hernia hyperviscoelasticity valence bond analysis |
| title | The effect of surface nucleation modulation on the mechanical and biocompatibility of metal-polymer biomaterials |
| title_full | The effect of surface nucleation modulation on the mechanical and biocompatibility of metal-polymer biomaterials |
| title_fullStr | The effect of surface nucleation modulation on the mechanical and biocompatibility of metal-polymer biomaterials |
| title_full_unstemmed | The effect of surface nucleation modulation on the mechanical and biocompatibility of metal-polymer biomaterials |
| title_short | The effect of surface nucleation modulation on the mechanical and biocompatibility of metal-polymer biomaterials |
| title_sort | effect of surface nucleation modulation on the mechanical and biocompatibility of metal polymer biomaterials |
| topic | nucleation analysis biomechanics hernia hyperviscoelasticity valence bond analysis |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1160351/full |
| work_keys_str_mv | AT zhenhongye theeffectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT zhenhongye theeffectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT lezhang theeffectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT taiweiliu theeffectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT weichengxuan theeffectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT xiaodonghe theeffectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT changhaohou theeffectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT donglinhan theeffectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT binbinyu theeffectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT junyeshi theeffectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT jiekang theeffectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT jiangpingchen theeffectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT jiangpingchen theeffectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT zhenhongye effectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT zhenhongye effectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT lezhang effectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT taiweiliu effectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT weichengxuan effectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT xiaodonghe effectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT changhaohou effectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT donglinhan effectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT binbinyu effectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT junyeshi effectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT jiekang effectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT jiangpingchen effectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials AT jiangpingchen effectofsurfacenucleationmodulationonthemechanicalandbiocompatibilityofmetalpolymerbiomaterials |