Comparison of docking procedures and its efficiency for Betasecretase, Aromatase and Pyruvate dehydrogenase kinase inhibitors

Comparison of docking procedures and its efficiency for Betasecretase, Aromatase and Pyruvate dehydrogenase kinase inhibitors

<p>Proper docking protocols were presented for three known enzyme structures, human betasecretase (BACE1), Aromatase and pyruvate dehydogenase kinase (PDHK) using Autodock4.2 and Vina softwares. The validity of docking protocols was verified using a set of known active ligands and decoys for a...

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Bibliographic Details
Main Authors: Zahra Rezaei, Masood Fereidoonnezhad, Zeinab Faghih, Hossein Sadeghpur, Ayyub Mojaddami, Amirhossein Sakhteman
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2017-03-01
Series:Trends in Pharmaceutical Sciences
Online Access:http://tips.sums.ac.ir/index.php/TiPS/article/view/116

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