Natural stilbenoids isolated from grapevine exhibiting inhibitory effects against HIV-1 integrase and eukaryote MOS1 transposase in vitro activities.

Natural stilbenoids isolated from grapevine exhibiting inhibitory effects against HIV-1 integrase and eukaryote MOS1 transposase in vitro activities.

Polynucleotidyl transferases are enzymes involved in several DNA mobility mechanisms in prokaryotes and eukaryotes. Some of them such as retroviral integrases are crucial for pathogenous processes and are therefore good candidates for therapeutic approaches. To identify new therapeutic compounds and...

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Bibliographic Details
Main Authors: Aude Pflieger, Pierre Waffo Teguo, Yorgos Papastamoulis, Stéphane Chaignepain, Frederic Subra, Soundasse Munir, Olivier Delelis, Paul Lesbats, Christina Calmels, Marie-Line Andreola, Jean-Michel Merillon, Corinne Auge-Gouillou, Vincent Parissi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3842960?pdf=render

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