Treatment of bladder cancer in the elderly
As the population ages and life expectancy increases in the human population, more individuals will be diagnosed with bladder cancer (BC). The definition of who is elderly is likely to change in the future from the commonly used cut-off of ≥75 years of age. Physiological rather than chronological...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Urological Association
2016-06-01
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| Series: | Investigative and Clinical Urology |
| Subjects: | |
| Online Access: | https://www.icurology.org/Synapse/Data/PDFData/2020ICU/icu-57-S26.pdf |
| _version_ | 1819083951652732928 |
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| author | Annette Erlich Alexandre R. Zlotta |
| author_facet | Annette Erlich Alexandre R. Zlotta |
| author_sort | Annette Erlich |
| collection | DOAJ |
| description | As the population ages and life expectancy increases in the human population, more individuals will be diagnosed with bladder
cancer (BC). The definition of who is elderly is likely to change in the future from the commonly used cut-off of ≥75 years of
age. Physiological rather than chronological age is key. BC care in the elderly is likely to become a very common problem in daily
practice. Concerns have been raised that senior BC patients are not given treatments that could cure their disease. Clinicians lack
quantitative and reliable estimates of competing mortality risks when considering treatments for BC. Majority of patients diagnosed
with BC are elderly, making treatment decisions complex with their increasing number of comorbidities. A multidisciplinary
approach to these patients may be a way to incorporate discussion from various disciplines regarding treatment options available.
Here we review various treatment options for elderly patients with muscle invasive BC and nonmuscle invasive BC. We include differences
in treatments from robotic versus open radical cystectomy, various urinary diversion techniques, chemotherapy, radiation
therapy and combination treatments. In clinical practice, treatment decisions for elderly patients should be done on a case-bycase
basis, tailored to each patient with their specific histories and comorbidities considered. Some healthy elderly patients may be
better candidates for extensive curative treatments than their younger counterparts. This implies that these important, life-altering
decisions cannot be solely based on age as many other factors can affect patient survival outcomes. |
| first_indexed | 2024-12-21T20:40:44Z |
| format | Article |
| id | doaj.art-ecca7af348ab4fe08362b23e9639c903 |
| institution | Directory Open Access Journal |
| issn | 2466-0493 2466-054X |
| language | English |
| last_indexed | 2024-12-21T20:40:44Z |
| publishDate | 2016-06-01 |
| publisher | Korean Urological Association |
| record_format | Article |
| series | Investigative and Clinical Urology |
| spelling | doaj.art-ecca7af348ab4fe08362b23e9639c9032022-12-21T18:50:59ZengKorean Urological AssociationInvestigative and Clinical Urology2466-04932466-054X2016-06-0157Suppl 1S26S3510.4111/icu.2016.57.S1.S26Treatment of bladder cancer in the elderlyAnnette Erlich0Alexandre R. Zlotta1Mount Sinai HospitalMount Sinai HospitalAs the population ages and life expectancy increases in the human population, more individuals will be diagnosed with bladder cancer (BC). The definition of who is elderly is likely to change in the future from the commonly used cut-off of ≥75 years of age. Physiological rather than chronological age is key. BC care in the elderly is likely to become a very common problem in daily practice. Concerns have been raised that senior BC patients are not given treatments that could cure their disease. Clinicians lack quantitative and reliable estimates of competing mortality risks when considering treatments for BC. Majority of patients diagnosed with BC are elderly, making treatment decisions complex with their increasing number of comorbidities. A multidisciplinary approach to these patients may be a way to incorporate discussion from various disciplines regarding treatment options available. Here we review various treatment options for elderly patients with muscle invasive BC and nonmuscle invasive BC. We include differences in treatments from robotic versus open radical cystectomy, various urinary diversion techniques, chemotherapy, radiation therapy and combination treatments. In clinical practice, treatment decisions for elderly patients should be done on a case-bycase basis, tailored to each patient with their specific histories and comorbidities considered. Some healthy elderly patients may be better candidates for extensive curative treatments than their younger counterparts. This implies that these important, life-altering decisions cannot be solely based on age as many other factors can affect patient survival outcomes.https://www.icurology.org/Synapse/Data/PDFData/2020ICU/icu-57-S26.pdfBladder cancer; Cystectomy; Elderly; Geriatric; Treatment |
| spellingShingle | Annette Erlich Alexandre R. Zlotta Treatment of bladder cancer in the elderly Investigative and Clinical Urology Bladder cancer; Cystectomy; Elderly; Geriatric; Treatment |
| title | Treatment of bladder cancer in the elderly |
| title_full | Treatment of bladder cancer in the elderly |
| title_fullStr | Treatment of bladder cancer in the elderly |
| title_full_unstemmed | Treatment of bladder cancer in the elderly |
| title_short | Treatment of bladder cancer in the elderly |
| title_sort | treatment of bladder cancer in the elderly |
| topic | Bladder cancer; Cystectomy; Elderly; Geriatric; Treatment |
| url | https://www.icurology.org/Synapse/Data/PDFData/2020ICU/icu-57-S26.pdf |
| work_keys_str_mv | AT annetteerlich treatmentofbladdercancerintheelderly AT alexandrerzlotta treatmentofbladdercancerintheelderly |