Predictors of death among severe COVID-19 patients admitted in Hawassa City, Sidama, Southern Ethiopia: Unmatched case-control study
<h4>Introduction</h4> Since COVID-19 was announced as a worldwide pandemic, the world has been struggling with this disease. In Ethiopia, there is some information on the epidemiological characteristics of the disease and treatment outcomes of COVID-19 patients. But, there is limited evi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2023-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977030/?tool=EBI |
| _version_ | 1811160124881895424 |
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| author | Samuel Misganaw Betelhem Eshetu Adugnaw Adane Tarekegn Solomon |
| author_facet | Samuel Misganaw Betelhem Eshetu Adugnaw Adane Tarekegn Solomon |
| author_sort | Samuel Misganaw |
| collection | DOAJ |
| description | <h4>Introduction</h4> Since COVID-19 was announced as a worldwide pandemic, the world has been struggling with this disease. In Ethiopia, there is some information on the epidemiological characteristics of the disease and treatment outcomes of COVID-19 patients. But, there is limited evidence related to predictors of death in COVID-19 patients. <h4>Objective</h4> To assess the predictor of death among severely ill COVID-19 patients admitted in Hawassa city COVID-19 treatment centers. <h4>Methods</h4> An institution-based unmatched case-control study was conducted at Hawassa city COVID-19 treatment centers from May 2021 to June 2021. All severe COVID-19-related deaths from May 2020 to May 2021 were included in the case group whereas randomly selected discharged severe COVID-19 patients were included in the control group. Extracted information was entered into Epi-data 4.6 and exported to SPSS 25 for analysis. Multivariable binary logistic regression was run to assess predictors. The result was presented as an adjusted odds ratio with a 95% confidence interval. Variables with a 95% confidence interval which not included one were considered statistically significant. <h4>Result</h4> A total of 372 (124 cases and 248 controls) patients were included in the study. Multivariable analysis revealed age ≥ 65 years (AOR = 2.62, 95% CI = 1.33–5.14), having shortness of breath (AOR = 1.87, 95% CI = 1.02–3.44), fatigue (AOR 1.78, 95% CI = 1.09–2.90), altered consciousness (AOR 3.02, 95% CI = 1.40, 6.49), diabetic Mellitus (AOR = 2.79, 95% CI = 1.16–6.73), chronic cerebrovascular disease (AOR = 2.1, 95% CI = 1.23, 3.88) were found to be predictors of death. <h4>Conclusion</h4> Older age, shortness of breath, fatigue, altered consciousness, and comorbidity were predictors of death in Severe COVID-19 patients. |
| first_indexed | 2024-04-10T05:53:26Z |
| format | Article |
| id | doaj.art-eccc2a761edc466d8f40b887c571c096 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-10T05:53:26Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-eccc2a761edc466d8f40b887c571c0962023-03-04T05:31:11ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01183Predictors of death among severe COVID-19 patients admitted in Hawassa City, Sidama, Southern Ethiopia: Unmatched case-control studySamuel MisganawBetelhem EshetuAdugnaw AdaneTarekegn Solomon<h4>Introduction</h4> Since COVID-19 was announced as a worldwide pandemic, the world has been struggling with this disease. In Ethiopia, there is some information on the epidemiological characteristics of the disease and treatment outcomes of COVID-19 patients. But, there is limited evidence related to predictors of death in COVID-19 patients. <h4>Objective</h4> To assess the predictor of death among severely ill COVID-19 patients admitted in Hawassa city COVID-19 treatment centers. <h4>Methods</h4> An institution-based unmatched case-control study was conducted at Hawassa city COVID-19 treatment centers from May 2021 to June 2021. All severe COVID-19-related deaths from May 2020 to May 2021 were included in the case group whereas randomly selected discharged severe COVID-19 patients were included in the control group. Extracted information was entered into Epi-data 4.6 and exported to SPSS 25 for analysis. Multivariable binary logistic regression was run to assess predictors. The result was presented as an adjusted odds ratio with a 95% confidence interval. Variables with a 95% confidence interval which not included one were considered statistically significant. <h4>Result</h4> A total of 372 (124 cases and 248 controls) patients were included in the study. Multivariable analysis revealed age ≥ 65 years (AOR = 2.62, 95% CI = 1.33–5.14), having shortness of breath (AOR = 1.87, 95% CI = 1.02–3.44), fatigue (AOR 1.78, 95% CI = 1.09–2.90), altered consciousness (AOR 3.02, 95% CI = 1.40, 6.49), diabetic Mellitus (AOR = 2.79, 95% CI = 1.16–6.73), chronic cerebrovascular disease (AOR = 2.1, 95% CI = 1.23, 3.88) were found to be predictors of death. <h4>Conclusion</h4> Older age, shortness of breath, fatigue, altered consciousness, and comorbidity were predictors of death in Severe COVID-19 patients.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977030/?tool=EBI |
| spellingShingle | Samuel Misganaw Betelhem Eshetu Adugnaw Adane Tarekegn Solomon Predictors of death among severe COVID-19 patients admitted in Hawassa City, Sidama, Southern Ethiopia: Unmatched case-control study PLoS ONE |
| title | Predictors of death among severe COVID-19 patients admitted in Hawassa City, Sidama, Southern Ethiopia: Unmatched case-control study |
| title_full | Predictors of death among severe COVID-19 patients admitted in Hawassa City, Sidama, Southern Ethiopia: Unmatched case-control study |
| title_fullStr | Predictors of death among severe COVID-19 patients admitted in Hawassa City, Sidama, Southern Ethiopia: Unmatched case-control study |
| title_full_unstemmed | Predictors of death among severe COVID-19 patients admitted in Hawassa City, Sidama, Southern Ethiopia: Unmatched case-control study |
| title_short | Predictors of death among severe COVID-19 patients admitted in Hawassa City, Sidama, Southern Ethiopia: Unmatched case-control study |
| title_sort | predictors of death among severe covid 19 patients admitted in hawassa city sidama southern ethiopia unmatched case control study |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9977030/?tool=EBI |
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