Type 2 Diabetes Mellitus in a 7 Year Old Girl
Basma Haris,1 Samuel Stafrace,2 Khalid Hussain1 1Department of Pediatric Endocrinology, Sidra Medicine, Doha, Qatar; 2Department of Diagnostic Imaging, Sidra Medicine, Doha, QatarCorrespondence: Khalid Hussain, Department of Pediatric Medicine, Sidra Medicine, OPC, C6-340|PO Box 26999, Al Luqta Stre...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2022-05-01
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| Series: | International Medical Case Reports Journal |
| Subjects: | |
| Online Access: | https://www.dovepress.com/type-2-diabetes-mellitus-in-a-7-year-old-girl-peer-reviewed-fulltext-article-IMCRJ |
| _version_ | 1817987435308515328 |
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| author | Haris B Stafrace S Hussain K |
| author_facet | Haris B Stafrace S Hussain K |
| author_sort | Haris B |
| collection | DOAJ |
| description | Basma Haris,1 Samuel Stafrace,2 Khalid Hussain1 1Department of Pediatric Endocrinology, Sidra Medicine, Doha, Qatar; 2Department of Diagnostic Imaging, Sidra Medicine, Doha, QatarCorrespondence: Khalid Hussain, Department of Pediatric Medicine, Sidra Medicine, OPC, C6-340|PO Box 26999, Al Luqta Street, Doha, Qatar, Tel +974-4003-7608 ; +974-30322007, Email khussain@sidra.orgAbstract: Type 2 diabetes is a chronic disease due to insulin resistance resulting in hyperglycemia. The prevalence of type 2 diabetes is increasing worldwide in the pediatric population. In the pediatric population, type 2 diabetes typically develops around adolescence; however, patients with a younger age of onset are now being reported. Earlier onset of type 2 diabetes is associated with a more aggressive course of disease and earlier comorbidities, although data on this is limited. We report a child from Qatar with type 2 diabetes that was diagnosed at 7 years of age, along obesity with a BMI of 26.8 kg/m2. Elevated liver enzymes, c-peptide, and insulin levels were observed along with fatty liver on an ultrasound. The child had severe acanthosis nigricans with increased appetite. There was a positive family history for type 2 diabetes. Testing for type 1 diabetes autoantibodies, monogenic obesity, and monogenic diabetes screening was negative. This is the second youngest child reported to have type 2 diabetes. Accurate diagnosis, early reporting, and long-term follow-up of such cases is necessary to bring more attention to the subgroup of type 2 diabetes in very young patients.Keywords: pediatric diabetes, type 2 diabetes, insulin resistance, early-onset diabetes mellitus |
| first_indexed | 2024-04-14T00:21:27Z |
| format | Article |
| id | doaj.art-eccf589eeb71409bb10922214e4b0238 |
| institution | Directory Open Access Journal |
| issn | 1179-142X |
| language | English |
| last_indexed | 2024-04-14T00:21:27Z |
| publishDate | 2022-05-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Medical Case Reports Journal |
| spelling | doaj.art-eccf589eeb71409bb10922214e4b02382022-12-22T02:22:56ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2022-05-01Volume 1524525075238Type 2 Diabetes Mellitus in a 7 Year Old GirlHaris BStafrace SHussain KBasma Haris,1 Samuel Stafrace,2 Khalid Hussain1 1Department of Pediatric Endocrinology, Sidra Medicine, Doha, Qatar; 2Department of Diagnostic Imaging, Sidra Medicine, Doha, QatarCorrespondence: Khalid Hussain, Department of Pediatric Medicine, Sidra Medicine, OPC, C6-340|PO Box 26999, Al Luqta Street, Doha, Qatar, Tel +974-4003-7608 ; +974-30322007, Email khussain@sidra.orgAbstract: Type 2 diabetes is a chronic disease due to insulin resistance resulting in hyperglycemia. The prevalence of type 2 diabetes is increasing worldwide in the pediatric population. In the pediatric population, type 2 diabetes typically develops around adolescence; however, patients with a younger age of onset are now being reported. Earlier onset of type 2 diabetes is associated with a more aggressive course of disease and earlier comorbidities, although data on this is limited. We report a child from Qatar with type 2 diabetes that was diagnosed at 7 years of age, along obesity with a BMI of 26.8 kg/m2. Elevated liver enzymes, c-peptide, and insulin levels were observed along with fatty liver on an ultrasound. The child had severe acanthosis nigricans with increased appetite. There was a positive family history for type 2 diabetes. Testing for type 1 diabetes autoantibodies, monogenic obesity, and monogenic diabetes screening was negative. This is the second youngest child reported to have type 2 diabetes. Accurate diagnosis, early reporting, and long-term follow-up of such cases is necessary to bring more attention to the subgroup of type 2 diabetes in very young patients.Keywords: pediatric diabetes, type 2 diabetes, insulin resistance, early-onset diabetes mellitushttps://www.dovepress.com/type-2-diabetes-mellitus-in-a-7-year-old-girl-peer-reviewed-fulltext-article-IMCRJpaediatric diabetestype 2 diabetesinsulin resistanceearly-onset diabetes mellitus |
| spellingShingle | Haris B Stafrace S Hussain K Type 2 Diabetes Mellitus in a 7 Year Old Girl International Medical Case Reports Journal paediatric diabetes type 2 diabetes insulin resistance early-onset diabetes mellitus |
| title | Type 2 Diabetes Mellitus in a 7 Year Old Girl |
| title_full | Type 2 Diabetes Mellitus in a 7 Year Old Girl |
| title_fullStr | Type 2 Diabetes Mellitus in a 7 Year Old Girl |
| title_full_unstemmed | Type 2 Diabetes Mellitus in a 7 Year Old Girl |
| title_short | Type 2 Diabetes Mellitus in a 7 Year Old Girl |
| title_sort | type 2 diabetes mellitus in a 7 year old girl |
| topic | paediatric diabetes type 2 diabetes insulin resistance early-onset diabetes mellitus |
| url | https://www.dovepress.com/type-2-diabetes-mellitus-in-a-7-year-old-girl-peer-reviewed-fulltext-article-IMCRJ |
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