SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS
We have analyzed the results of combined clinical laboratory study in 100 patients, in whom abdominal sepsis was diagnosed. Along with a standard protocol of medical and diagnostic measures, all the patients underwent immunological examination, i.e., populations and subpopulations of immunocompetent...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/102 |
| _version_ | 1826534355071139840 |
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| author | V. V. Grebenuyk N. V. Yusan |
| author_facet | V. V. Grebenuyk N. V. Yusan |
| author_sort | V. V. Grebenuyk |
| collection | DOAJ |
| description | We have analyzed the results of combined clinical laboratory study in 100 patients, in whom abdominal sepsis was diagnosed. Along with a standard protocol of medical and diagnostic measures, all the patients underwent immunological examination, i.e., populations and subpopulations of immunocompetent cells were defined by indirect immunofluorescence method, immunoglobulins of main types, and serum cytokines were defined by means of immune-enzyme assay. Immunoregulatory index and levels of IL-1ra in blood serum significantly correlated with severe state and disease outcomes in the patients with abdominal sepsis. Due to such characteristic features, the CD4+/CD8+ ratio and IL-1ra level were are included into a proposed list of parameters able to predict fatal outcome in the patients with abdominal sepsis. |
| first_indexed | 2024-03-08T05:52:07Z |
| format | Article |
| id | doaj.art-eccf75df63bd4fc886856e8d71af4ea3 |
| institution | Directory Open Access Journal |
| issn | 1563-0625 2313-741X |
| language | Russian |
| last_indexed | 2025-03-14T02:21:42Z |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj.art-eccf75df63bd4fc886856e8d71af4ea32025-03-11T17:59:00ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0112325325810.15789/1563-0625-2010-3-253-25899SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSISV. V. Grebenuyk0N. V. Yusan1ГОУ ВПО «Амурская государственная медицинская академия», г. БлаговещенскГОУ ВПО «Амурская государственная медицинская академия», г. БлаговещенскWe have analyzed the results of combined clinical laboratory study in 100 patients, in whom abdominal sepsis was diagnosed. Along with a standard protocol of medical and diagnostic measures, all the patients underwent immunological examination, i.e., populations and subpopulations of immunocompetent cells were defined by indirect immunofluorescence method, immunoglobulins of main types, and serum cytokines were defined by means of immune-enzyme assay. Immunoregulatory index and levels of IL-1ra in blood serum significantly correlated with severe state and disease outcomes in the patients with abdominal sepsis. Due to such characteristic features, the CD4+/CD8+ ratio and IL-1ra level were are included into a proposed list of parameters able to predict fatal outcome in the patients with abdominal sepsis.https://www.mimmun.ru/mimmun/article/view/102abdominal sepsissepsis predictionlymphocytesimmune regulation indexil-1ra |
| spellingShingle | V. V. Grebenuyk N. V. Yusan SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS Медицинская иммунология abdominal sepsis sepsis prediction lymphocytes immune regulation index il-1ra |
| title | SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS |
| title_full | SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS |
| title_fullStr | SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS |
| title_full_unstemmed | SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS |
| title_short | SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS |
| title_sort | significance of immune indexes in severity evaluation in the patients with abdominal sepsis |
| topic | abdominal sepsis sepsis prediction lymphocytes immune regulation index il-1ra |
| url | https://www.mimmun.ru/mimmun/article/view/102 |
| work_keys_str_mv | AT vvgrebenuyk significanceofimmuneindexesinseverityevaluationinthepatientswithabdominalsepsis AT nvyusan significanceofimmuneindexesinseverityevaluationinthepatientswithabdominalsepsis |