Serine Phosphorylation of L-Selectin Regulates ERM Binding, Clustering, and Monocyte Protrusion in Transendothelial Migration
The migration of circulating leukocytes toward damaged tissue is absolutely fundamental to the inflammatory response, and transendothelial migration (TEM) describes the first cellular barrier that is breached in this process. Human CD14+ inflammatory monocytes express L-selectin, bestowing a non-can...
Main Authors: | Abigail Newe, Karolina Rzeniewicz, Melanie König, Carsten F. E. Schroer, Justin Joachim, Angela Rey-Gallardo, Siewert J. Marrink, Jürgen Deka, Maddy Parsons, Aleksandar Ivetic |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-09-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2019.02227/full |
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