An update on the coronary calcium score: a review for clinicians

The clinical manifestation of coronary artery atherosclerosis is coronary artery disease (CAD) with symptoms ranging from exertional chest pain due to reduction of coronary flow reserve to acute coronary syndrome due to rupture of usually a nonobstructive plaque with abrupt coronary blood flow reduc...

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Main Authors: Monika Czaja-Ziółkowska, Jarosław Wasilewski, Mariusz Gąsior, Jan Głowacki
Format: Article
Language:English
Published: Termedia Publishing House 2022-12-01
Series:Advances in Interventional Cardiology
Subjects:
Online Access:https://www.termedia.pl/An-update-on-the-coronary-calcium-score-a-review-for-clinicians,35,48150,1,1.html
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author Monika Czaja-Ziółkowska
Jarosław Wasilewski
Mariusz Gąsior
Jan Głowacki
author_facet Monika Czaja-Ziółkowska
Jarosław Wasilewski
Mariusz Gąsior
Jan Głowacki
author_sort Monika Czaja-Ziółkowska
collection DOAJ
description The clinical manifestation of coronary artery atherosclerosis is coronary artery disease (CAD) with symptoms ranging from exertional chest pain due to reduction of coronary flow reserve to acute coronary syndrome due to rupture of usually a nonobstructive plaque with abrupt coronary blood flow reduction. CAD is the leading cause of morbidity and mortality worldwide. Therefore, identifying asymptomatic people at risk of CAD is pivotal to guide decision-making for primary prevention. Coronary artery calcium (CAC) is a hallmark of coronary artery atherosclerosis. It can be detected using cardiac computed tomography and quantified by the Agatston method. CAC examination is a cheap, fast and low radiation dose test, without injecting a contrast agent. It provides prognostic information over other traditional cardiovascular risk markers and established scoring systems, especially for low-risk subgroups such as women and younger adults, and indicates the appropriate moment to implement primary prevention, including acetylsalicylic acid and statins. In this review, we discuss the methods of CAC evaluation, the meaning of a zero CAC score (CACS), its conversion to CACS > 0 and the impact of this fact on cardiovascular risk, the effect of statins and proprotein convertase subtilisin/kexin type 9 inhibitor on CAC progression, interpretation of CACS results, and CACS prognostic value in both asymptomatic and symptomatic patients.
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spelling doaj.art-ecd0087633c2468794d95c6df4f3a5e12023-12-01T13:40:58ZengTermedia Publishing HouseAdvances in Interventional Cardiology1734-93381897-42952022-12-0118320120510.5114/aic.2022.12103548150An update on the coronary calcium score: a review for cliniciansMonika Czaja-ZiółkowskaJarosław WasilewskiMariusz GąsiorJan GłowackiThe clinical manifestation of coronary artery atherosclerosis is coronary artery disease (CAD) with symptoms ranging from exertional chest pain due to reduction of coronary flow reserve to acute coronary syndrome due to rupture of usually a nonobstructive plaque with abrupt coronary blood flow reduction. CAD is the leading cause of morbidity and mortality worldwide. Therefore, identifying asymptomatic people at risk of CAD is pivotal to guide decision-making for primary prevention. Coronary artery calcium (CAC) is a hallmark of coronary artery atherosclerosis. It can be detected using cardiac computed tomography and quantified by the Agatston method. CAC examination is a cheap, fast and low radiation dose test, without injecting a contrast agent. It provides prognostic information over other traditional cardiovascular risk markers and established scoring systems, especially for low-risk subgroups such as women and younger adults, and indicates the appropriate moment to implement primary prevention, including acetylsalicylic acid and statins. In this review, we discuss the methods of CAC evaluation, the meaning of a zero CAC score (CACS), its conversion to CACS > 0 and the impact of this fact on cardiovascular risk, the effect of statins and proprotein convertase subtilisin/kexin type 9 inhibitor on CAC progression, interpretation of CACS results, and CACS prognostic value in both asymptomatic and symptomatic patients.https://www.termedia.pl/An-update-on-the-coronary-calcium-score-a-review-for-clinicians,35,48150,1,1.htmlcomputed tomography coronary artery calcium coronary artery disease
spellingShingle Monika Czaja-Ziółkowska
Jarosław Wasilewski
Mariusz Gąsior
Jan Głowacki
An update on the coronary calcium score: a review for clinicians
Advances in Interventional Cardiology
computed tomography
coronary artery calcium
coronary artery disease
title An update on the coronary calcium score: a review for clinicians
title_full An update on the coronary calcium score: a review for clinicians
title_fullStr An update on the coronary calcium score: a review for clinicians
title_full_unstemmed An update on the coronary calcium score: a review for clinicians
title_short An update on the coronary calcium score: a review for clinicians
title_sort update on the coronary calcium score a review for clinicians
topic computed tomography
coronary artery calcium
coronary artery disease
url https://www.termedia.pl/An-update-on-the-coronary-calcium-score-a-review-for-clinicians,35,48150,1,1.html
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