Abnormal regulation of glucagon secretion by human islet alpha cells in the absence of beta cells

Abnormal regulation of glucagon secretion by human islet alpha cells in the absence of beta cells

Background: The understanding of the regulation of glucagon secretion by pancreatic islet α-cells remains elusive. We aimed to develop an in vitro model for investigating the function of human α-cells under direct influence of glucose and other potential regulators. Methods: Highly purified human α-...

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Bibliographic Details
Main Authors:	Wei Liu, Tatsuya Kin, Siuhong Ho, Craig Dorrell, Sean R. Campbell, Ping Luo, Xiaojuan Chen
Format:	Article
Language:	English
Published:	Elsevier 2019-12-01
Series:	EBioMedicine
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396419307674

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