Studying Autism Spectrum Disorder with Structural and Diffusion Magnetic Resonance Imaging: A Survey
Magnetic resonance imaging (MRI) modalities have emerged as powerful means that facilitatenon-invasive clinical diagnostics of various diseases and abnormalities since their inception in the1980s. Multiple MRI modalities, such as different types of the sMRI and DTI, have been employedto investigate...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-05-01
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| Series: | Frontiers in Human Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnhum.2016.00211/full |
| _version_ | 1828941304661278720 |
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| author | Marwa Maher Tawfik Ismail Robert S. Keynton Mahmoud Mohamed Mahmoud Osman Mostapha Ahmed Hazem ElTanboly Manuel Fernando Casanova Georgy L Gimel'farb Ayman eEl-Baz |
| author_facet | Marwa Maher Tawfik Ismail Robert S. Keynton Mahmoud Mohamed Mahmoud Osman Mostapha Ahmed Hazem ElTanboly Manuel Fernando Casanova Georgy L Gimel'farb Ayman eEl-Baz |
| author_sort | Marwa Maher Tawfik Ismail |
| collection | DOAJ |
| description | Magnetic resonance imaging (MRI) modalities have emerged as powerful means that facilitatenon-invasive clinical diagnostics of various diseases and abnormalities since their inception in the1980s. Multiple MRI modalities, such as different types of the sMRI and DTI, have been employedto investigate facets of ASD in order to better understand this complex syndrome. This paperreviews recent applications of structural magnetic resonance imaging (sMRI) and diffusion tensorimaging (DTI), to study autism spectrum disorder (ASD). Main reported findings are sometimescontradictory due to different age ranges, hardware protocols, population types, numbers of participants,and image analysis parameters. The primary anatomical structures, such as amygdalae,cerebrum, and cerebellum, associated with clinical-pathological correlates of ASD are highlightedthrough successive life stages, from infancy to adulthood. This survey demonstrates the absenceof consistent pathology in the brains of autistic children and lack of research investigations in patientsunder two years of age in the literature. The known publications also emphasize advancesin data acquisition and analysis, as well as significance of multimodal approaches that combineresting-state, task-evoked, and sMRI measures. Initial results obtained with the sMRI and DTIshow good promise towards the early and non-invasive ASD diagnostics. |
| first_indexed | 2024-12-14T03:34:34Z |
| format | Article |
| id | doaj.art-ecd52c06a6b94cfaa329f79d9ef74f92 |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-12-14T03:34:34Z |
| publishDate | 2016-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-ecd52c06a6b94cfaa329f79d9ef74f922022-12-21T23:18:39ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612016-05-011010.3389/fnhum.2016.00211184484Studying Autism Spectrum Disorder with Structural and Diffusion Magnetic Resonance Imaging: A SurveyMarwa Maher Tawfik Ismail0Robert S. Keynton1Mahmoud Mohamed Mahmoud Osman Mostapha2Ahmed Hazem ElTanboly3Manuel Fernando Casanova4Georgy L Gimel'farb5Ayman eEl-Baz6University of LouisvilleUniversity of LouisvilleUniversity of LouisvilleUniversity of LouisvilleUniversity of South CarloinaUniversity of AucklandUniversity of LouisvilleMagnetic resonance imaging (MRI) modalities have emerged as powerful means that facilitatenon-invasive clinical diagnostics of various diseases and abnormalities since their inception in the1980s. Multiple MRI modalities, such as different types of the sMRI and DTI, have been employedto investigate facets of ASD in order to better understand this complex syndrome. This paperreviews recent applications of structural magnetic resonance imaging (sMRI) and diffusion tensorimaging (DTI), to study autism spectrum disorder (ASD). Main reported findings are sometimescontradictory due to different age ranges, hardware protocols, population types, numbers of participants,and image analysis parameters. The primary anatomical structures, such as amygdalae,cerebrum, and cerebellum, associated with clinical-pathological correlates of ASD are highlightedthrough successive life stages, from infancy to adulthood. This survey demonstrates the absenceof consistent pathology in the brains of autistic children and lack of research investigations in patientsunder two years of age in the literature. The known publications also emphasize advancesin data acquisition and analysis, as well as significance of multimodal approaches that combineresting-state, task-evoked, and sMRI measures. Initial results obtained with the sMRI and DTIshow good promise towards the early and non-invasive ASD diagnostics.http://journal.frontiersin.org/Journal/10.3389/fnhum.2016.00211/fullautismDiffusion Tensor MRIstructural MRImulti-modal approachesLife stages. |
| spellingShingle | Marwa Maher Tawfik Ismail Robert S. Keynton Mahmoud Mohamed Mahmoud Osman Mostapha Ahmed Hazem ElTanboly Manuel Fernando Casanova Georgy L Gimel'farb Ayman eEl-Baz Studying Autism Spectrum Disorder with Structural and Diffusion Magnetic Resonance Imaging: A Survey Frontiers in Human Neuroscience autism Diffusion Tensor MRI structural MRI multi-modal approaches Life stages. |
| title | Studying Autism Spectrum Disorder with Structural and Diffusion Magnetic Resonance Imaging: A Survey |
| title_full | Studying Autism Spectrum Disorder with Structural and Diffusion Magnetic Resonance Imaging: A Survey |
| title_fullStr | Studying Autism Spectrum Disorder with Structural and Diffusion Magnetic Resonance Imaging: A Survey |
| title_full_unstemmed | Studying Autism Spectrum Disorder with Structural and Diffusion Magnetic Resonance Imaging: A Survey |
| title_short | Studying Autism Spectrum Disorder with Structural and Diffusion Magnetic Resonance Imaging: A Survey |
| title_sort | studying autism spectrum disorder with structural and diffusion magnetic resonance imaging a survey |
| topic | autism Diffusion Tensor MRI structural MRI multi-modal approaches Life stages. |
| url | http://journal.frontiersin.org/Journal/10.3389/fnhum.2016.00211/full |
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