The eternal quest for self-improvement of somatic cells
Summary: Multiple somatic mutations drive cancer cell transformation, but the sequence of events is poorly understood. In this issue of Cell Genomics, Kester et al. combine organoid technology, prospective barcode labeling, and single-cell sequencing to study the evolution of somatic clones in vitro...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-02-01
|
| Series: | Cell Genomics |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666979X22000118 |
| _version_ | 1797776691225952256 |
|---|---|
| author | Peter J. Campbell |
| author_facet | Peter J. Campbell |
| author_sort | Peter J. Campbell |
| collection | DOAJ |
| description | Summary: Multiple somatic mutations drive cancer cell transformation, but the sequence of events is poorly understood. In this issue of Cell Genomics, Kester et al. combine organoid technology, prospective barcode labeling, and single-cell sequencing to study the evolution of somatic clones in vitro. |
| first_indexed | 2024-03-12T22:53:30Z |
| format | Article |
| id | doaj.art-ecd62ba799e94a1fbe5cea55bc60c475 |
| institution | Directory Open Access Journal |
| issn | 2666-979X |
| language | English |
| last_indexed | 2024-03-12T22:53:30Z |
| publishDate | 2022-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cell Genomics |
| spelling | doaj.art-ecd62ba799e94a1fbe5cea55bc60c4752023-07-20T04:39:15ZengElsevierCell Genomics2666-979X2022-02-0122100094The eternal quest for self-improvement of somatic cellsPeter J. Campbell0Wellcome Sanger Institute, Hinxton CB10 1SA, UK; Corresponding authorSummary: Multiple somatic mutations drive cancer cell transformation, but the sequence of events is poorly understood. In this issue of Cell Genomics, Kester et al. combine organoid technology, prospective barcode labeling, and single-cell sequencing to study the evolution of somatic clones in vitro.http://www.sciencedirect.com/science/article/pii/S2666979X22000118 |
| spellingShingle | Peter J. Campbell The eternal quest for self-improvement of somatic cells Cell Genomics |
| title | The eternal quest for self-improvement of somatic cells |
| title_full | The eternal quest for self-improvement of somatic cells |
| title_fullStr | The eternal quest for self-improvement of somatic cells |
| title_full_unstemmed | The eternal quest for self-improvement of somatic cells |
| title_short | The eternal quest for self-improvement of somatic cells |
| title_sort | eternal quest for self improvement of somatic cells |
| url | http://www.sciencedirect.com/science/article/pii/S2666979X22000118 |
| work_keys_str_mv | AT peterjcampbell theeternalquestforselfimprovementofsomaticcells AT peterjcampbell eternalquestforselfimprovementofsomaticcells |