Comparison of survival outcomes between modified radical mastectomy and breast conserving surgery in early breast cancer patients
Abstract Objectives Breast conserving surgery (BCS) for early breast cancer is now an accepted treatment, but there are controversies about its comparability with mastectomy. Thus, we investigated the survival outcomes who underwent BCS and modified radical mastectomy (MRM). Methods In this retrospe...
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| Format: | Article |
| Language: | English |
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Kosin University College of Medicine
2016-06-01
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| Series: | Kosin Medical Journal |
| Subjects: | |
| Online Access: | http://www.kosinmedj.org/upload/pdf/ksmc031-01-03.pdf |
| _version_ | 1811255755435671552 |
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| author | Yoon Seok Kim Dong Won Ryu Chung Han Lee |
| author_facet | Yoon Seok Kim Dong Won Ryu Chung Han Lee |
| author_sort | Yoon Seok Kim |
| collection | DOAJ |
| description | Abstract Objectives Breast conserving surgery (BCS) for early breast cancer is now an accepted treatment, but there are controversies about its comparability with mastectomy. Thus, we investigated the survival outcomes who underwent BCS and modified radical mastectomy (MRM). Methods In this retrospective review, we analyzed the survival outcomes of 618 patients with early breast cancer who underwent two different surgery from January 2002 to December 2009. Postoperative pathologic difference, disease free survival period, overall survival period, recurrence pattern, recurrent rate and site were compared. In addition, preoperative patients data are also collected. Results Disease free survival period of MRM and BCS was 108.46 months and 80.82 months, respectively (P< 0.01). However, there was no significant correlation between overall survival period and operative methods (P= 0.67). In addition, recurrence pattern (P= 0.21), recurrent rate (P= 0.36) and site (P= 0.45, P= 0.09) were not associated with operative method. Conclusions In this study, we can suggest that early breast cancer patients could improve their disease free survival if they underwent MRM. So, when we operate high risk breast cancer patients, MRM could be considered for their disease free life. Further studies may be required to establish appropriate strategy of surgery for early breast cancer. |
| first_indexed | 2024-04-12T17:29:39Z |
| format | Article |
| id | doaj.art-ecd733bf2458402a860f60aac0233c8b |
| institution | Directory Open Access Journal |
| issn | 2005-9531 2586-7024 |
| language | English |
| last_indexed | 2024-04-12T17:29:39Z |
| publishDate | 2016-06-01 |
| publisher | Kosin University College of Medicine |
| record_format | Article |
| series | Kosin Medical Journal |
| spelling | doaj.art-ecd733bf2458402a860f60aac0233c8b2022-12-22T03:23:11ZengKosin University College of MedicineKosin Medical Journal2005-95312586-70242016-06-01311192910.7180/kmj.2016.31.1.191164Comparison of survival outcomes between modified radical mastectomy and breast conserving surgery in early breast cancer patientsYoon Seok Kim0Dong Won Ryu1Chung Han Lee2Department of Surgery, Busan adventist Hospital, Busan, KoreaDepartment of Surgery, College of Medicine, Kosin University, Busan, KoreaDepartment of Surgery, College of Medicine, Kosin University, Busan, KoreaAbstract Objectives Breast conserving surgery (BCS) for early breast cancer is now an accepted treatment, but there are controversies about its comparability with mastectomy. Thus, we investigated the survival outcomes who underwent BCS and modified radical mastectomy (MRM). Methods In this retrospective review, we analyzed the survival outcomes of 618 patients with early breast cancer who underwent two different surgery from January 2002 to December 2009. Postoperative pathologic difference, disease free survival period, overall survival period, recurrence pattern, recurrent rate and site were compared. In addition, preoperative patients data are also collected. Results Disease free survival period of MRM and BCS was 108.46 months and 80.82 months, respectively (P< 0.01). However, there was no significant correlation between overall survival period and operative methods (P= 0.67). In addition, recurrence pattern (P= 0.21), recurrent rate (P= 0.36) and site (P= 0.45, P= 0.09) were not associated with operative method. Conclusions In this study, we can suggest that early breast cancer patients could improve their disease free survival if they underwent MRM. So, when we operate high risk breast cancer patients, MRM could be considered for their disease free life. Further studies may be required to establish appropriate strategy of surgery for early breast cancer.http://www.kosinmedj.org/upload/pdf/ksmc031-01-03.pdfbreast conserving surgerydisease free survivalearly breast cancermodified radical mastectomy |
| spellingShingle | Yoon Seok Kim Dong Won Ryu Chung Han Lee Comparison of survival outcomes between modified radical mastectomy and breast conserving surgery in early breast cancer patients Kosin Medical Journal breast conserving surgery disease free survival early breast cancer modified radical mastectomy |
| title | Comparison of survival outcomes between modified radical mastectomy and breast conserving surgery in early breast cancer patients |
| title_full | Comparison of survival outcomes between modified radical mastectomy and breast conserving surgery in early breast cancer patients |
| title_fullStr | Comparison of survival outcomes between modified radical mastectomy and breast conserving surgery in early breast cancer patients |
| title_full_unstemmed | Comparison of survival outcomes between modified radical mastectomy and breast conserving surgery in early breast cancer patients |
| title_short | Comparison of survival outcomes between modified radical mastectomy and breast conserving surgery in early breast cancer patients |
| title_sort | comparison of survival outcomes between modified radical mastectomy and breast conserving surgery in early breast cancer patients |
| topic | breast conserving surgery disease free survival early breast cancer modified radical mastectomy |
| url | http://www.kosinmedj.org/upload/pdf/ksmc031-01-03.pdf |
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