A Narrative Review of <sup>99m</sup>Tc-Aprotinin in the Diagnosis of Cardiac Amyloidosis and a New Life for an Unfairly Abandoned Drug
Several studies investigated the use of <sup>99m</sup>Tc-labelled Aprotinin as an amyloid seeker some years ago. In vitro tests showed high binding affinity for several types of amyloid fibrils accompanied by an excellent specificity. Initial human studies demonstrated good accuracy in d...
Main Authors: | Carlo Aprile, Lorenzo Lodola |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-06-01
|
Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/10/6/1377 |
Similar Items
-
Effect of Aprotinin and Avifavir<sup>®</sup> Combination Therapy for Moderate COVID-19 Patients
by: Andrey A. Ivashchenko, et al.
Published: (2021-06-01) -
Extracellular serine-proteinases isolated from Streptomyces alboniger: Partial characterization and effect of aprotinin on cellular structure
by: Lopes Andréa, et al.
Published: (1999-01-01) -
Effect of Aprotinin on Liver Injury after Transplantation of Extended Criteria Donor Grafts in Humans: A Retrospective Propensity Score Matched Cohort Analysis
by: Anna B. Roehl, et al.
Published: (2021-11-01) -
Modulation of thromboinflammation in hospitalized COVID‐19 patients with aprotinin, low molecular weight heparin, and anakinra: The DAWn‐Antico study
by: Matthias M. Engelen, et al.
Published: (2022-10-01) -
The Efficacy of Aprotinin Combinations with Selected Antiviral Drugs in Mouse Models of Influenza Pneumonia and Coronavirus Infection Caused by SARS-CoV-2
by: Andrey A. Ivashchenko, et al.
Published: (2022-08-01)