Graphene quantum dots as nanoprobes for fluorescent detection of propofol in emulsions
We report a new fluorescent detection method for propofol based on graphene quantum dots (GQDs). Citric acid (CA) was selected as the carbon precursor, and fluorescent GQDs were prepared by carbonizing CA. The product, which efficiently quenched the fluorescence of GQDs, could be obtained through th...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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The Royal Society
2019-01-01
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| Series: | Royal Society Open Science |
| Subjects: | |
| Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.181753 |
| _version_ | 1828468346948943872 |
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| author | Juanjuan Diao Tingting Wang Li Li |
| author_facet | Juanjuan Diao Tingting Wang Li Li |
| author_sort | Juanjuan Diao |
| collection | DOAJ |
| description | We report a new fluorescent detection method for propofol based on graphene quantum dots (GQDs). Citric acid (CA) was selected as the carbon precursor, and fluorescent GQDs were prepared by carbonizing CA. The product, which efficiently quenched the fluorescence of GQDs, could be obtained through the oxidation of propofol in the presence of horseradish peroxidase and hydrogen peroxide. The fluorescence intensity ratio of GQDs (F/F0) was positively correlated with the concentration of propofol, which ranged within 5.34–89.07 mg l−1, the limit of detection was 0.5 mg l−1 and the limit of quantity was 5.34 mg l−1. The developed fluorescence method reported in the present study is simple, sensitive, reproducible, and can serve in determining propofol contents in emulsions. |
| first_indexed | 2024-12-11T04:21:56Z |
| format | Article |
| id | doaj.art-ecde369056a04b289689b67ef143db52 |
| institution | Directory Open Access Journal |
| issn | 2054-5703 |
| language | English |
| last_indexed | 2024-12-11T04:21:56Z |
| publishDate | 2019-01-01 |
| publisher | The Royal Society |
| record_format | Article |
| series | Royal Society Open Science |
| spelling | doaj.art-ecde369056a04b289689b67ef143db522022-12-22T01:21:06ZengThe Royal SocietyRoyal Society Open Science2054-57032019-01-016110.1098/rsos.181753181753Graphene quantum dots as nanoprobes for fluorescent detection of propofol in emulsionsJuanjuan DiaoTingting WangLi LiWe report a new fluorescent detection method for propofol based on graphene quantum dots (GQDs). Citric acid (CA) was selected as the carbon precursor, and fluorescent GQDs were prepared by carbonizing CA. The product, which efficiently quenched the fluorescence of GQDs, could be obtained through the oxidation of propofol in the presence of horseradish peroxidase and hydrogen peroxide. The fluorescence intensity ratio of GQDs (F/F0) was positively correlated with the concentration of propofol, which ranged within 5.34–89.07 mg l−1, the limit of detection was 0.5 mg l−1 and the limit of quantity was 5.34 mg l−1. The developed fluorescence method reported in the present study is simple, sensitive, reproducible, and can serve in determining propofol contents in emulsions.https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.181753graphene quantum dotspropofolfluorescenceemulsions |
| spellingShingle | Juanjuan Diao Tingting Wang Li Li Graphene quantum dots as nanoprobes for fluorescent detection of propofol in emulsions Royal Society Open Science graphene quantum dots propofol fluorescence emulsions |
| title | Graphene quantum dots as nanoprobes for fluorescent detection of propofol in emulsions |
| title_full | Graphene quantum dots as nanoprobes for fluorescent detection of propofol in emulsions |
| title_fullStr | Graphene quantum dots as nanoprobes for fluorescent detection of propofol in emulsions |
| title_full_unstemmed | Graphene quantum dots as nanoprobes for fluorescent detection of propofol in emulsions |
| title_short | Graphene quantum dots as nanoprobes for fluorescent detection of propofol in emulsions |
| title_sort | graphene quantum dots as nanoprobes for fluorescent detection of propofol in emulsions |
| topic | graphene quantum dots propofol fluorescence emulsions |
| url | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.181753 |
| work_keys_str_mv | AT juanjuandiao graphenequantumdotsasnanoprobesforfluorescentdetectionofpropofolinemulsions AT tingtingwang graphenequantumdotsasnanoprobesforfluorescentdetectionofpropofolinemulsions AT lili graphenequantumdotsasnanoprobesforfluorescentdetectionofpropofolinemulsions |