Nasal immunization with H7 flagellin protects mice against hemolytic uremic syndrome secondary to Escherichia coli O157:H7 gastrointestinal infection

Nasal immunization with H7 flagellin protects mice against hemolytic uremic syndrome secondary to Escherichia coli O157:H7 gastrointestinal infection

IntroductionShiga-toxin (Stx) producing Escherichia coli (STEC) O157:H7 is the most frequent serotype associated with hemolytic uremic syndrome (HUS) after gastrointestinal infections. Protection against HUS secondary to STEC infections has been experimentally assayed through the generation of diffe...

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Bibliographic Details
Main Authors: Alan Mauro Bernal, Fernando Nicolás Sosa, María Florencia Todero, Daniela Romina Montagna, Mónica Elba Vermeulen, Romina Jimena Fernández-Brando, María Victoria Ramos, Agustina Juliana Errea, Martin Rumbo, Marina Sandra Palermo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Shiga toxin-producing Escherichia coli
intestinal infection
HUS
flagellin
immunization
mouse model
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1143918/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2023.1143918/full

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