Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development

Aspergillosis is a common fungal infection with systemic characteristics, which is caused by various species of Aspergillus. The infection could develop in immunocompromised and immunocompetent patients under specific circumstances. Based on the clinical features and type of invasion, aspergillosis...

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Main Author: Ali AL-Janabi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2020-03-01
Series:Reviews in Clinical Medicine
Subjects:
Online Access:https://rcm.mums.ac.ir/article_15121_2838ee381264db9cf0abaa51852a3c8a.pdf
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author Ali AL-Janabi
author_facet Ali AL-Janabi
author_sort Ali AL-Janabi
collection DOAJ
description Aspergillosis is a common fungal infection with systemic characteristics, which is caused by various species of Aspergillus. The infection could develop in immunocompromised and immunocompetent patients under specific circumstances. Based on the clinical features and type of invasion, aspergillosis could be classified into four main categories, including invasive pulmonary aspergillosis (IPA), noninvasive aspergilloma, semi-invasive chronic pulmonary aspergillosis, and allergic bronchopulmonary aspergillosis (ABPA). Treatment with immunosuppressive drugs for inflammatory diseases, such as rheumatoid arthritis (RA), increases the infection rate with aspergillosis. RA is an autoimmune disease characterized by several chronic symptoms in the joints, including pain, stiffness, and chronic synovitis. Previous studies have denoted an association between RA and aspergillosis. Inhibitory drugs of tumor necrosis factors and steroids are widely used in the treatment of RA. ABPA and IPA are the most commonly diagnosed diseases in patients with RA. The present study aimed to review the effects of RA and its treatment on the development of aspergillosis.
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spelling doaj.art-ece586949bb040219eaf2ba089733a8d2022-12-27T13:05:41ZengMashhad University of Medical SciencesReviews in Clinical Medicine2345-62562345-68922020-03-016415516410.22038/rcm.2020.45709.130215121Therapeutic effects of Rheumatoid Arthritis on Aspergillosis developmentAli AL-Janabi0Department of Microbiology, College of Medicine, University of Karbala, Karbala,Iraq.Aspergillosis is a common fungal infection with systemic characteristics, which is caused by various species of Aspergillus. The infection could develop in immunocompromised and immunocompetent patients under specific circumstances. Based on the clinical features and type of invasion, aspergillosis could be classified into four main categories, including invasive pulmonary aspergillosis (IPA), noninvasive aspergilloma, semi-invasive chronic pulmonary aspergillosis, and allergic bronchopulmonary aspergillosis (ABPA). Treatment with immunosuppressive drugs for inflammatory diseases, such as rheumatoid arthritis (RA), increases the infection rate with aspergillosis. RA is an autoimmune disease characterized by several chronic symptoms in the joints, including pain, stiffness, and chronic synovitis. Previous studies have denoted an association between RA and aspergillosis. Inhibitory drugs of tumor necrosis factors and steroids are widely used in the treatment of RA. ABPA and IPA are the most commonly diagnosed diseases in patients with RA. The present study aimed to review the effects of RA and its treatment on the development of aspergillosis.https://rcm.mums.ac.ir/article_15121_2838ee381264db9cf0abaa51852a3c8a.pdfaspergillomaaspergillosisrheumatoid arthritistnf inhibitors
spellingShingle Ali AL-Janabi
Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development
Reviews in Clinical Medicine
aspergilloma
aspergillosis
rheumatoid arthritis
tnf inhibitors
title Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development
title_full Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development
title_fullStr Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development
title_full_unstemmed Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development
title_short Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development
title_sort therapeutic effects of rheumatoid arthritis on aspergillosis development
topic aspergilloma
aspergillosis
rheumatoid arthritis
tnf inhibitors
url https://rcm.mums.ac.ir/article_15121_2838ee381264db9cf0abaa51852a3c8a.pdf
work_keys_str_mv AT alialjanabi therapeuticeffectsofrheumatoidarthritisonaspergillosisdevelopment