Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development
Aspergillosis is a common fungal infection with systemic characteristics, which is caused by various species of Aspergillus. The infection could develop in immunocompromised and immunocompetent patients under specific circumstances. Based on the clinical features and type of invasion, aspergillosis...
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Format: | Article |
Language: | English |
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Mashhad University of Medical Sciences
2020-03-01
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Series: | Reviews in Clinical Medicine |
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Online Access: | https://rcm.mums.ac.ir/article_15121_2838ee381264db9cf0abaa51852a3c8a.pdf |
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author | Ali AL-Janabi |
author_facet | Ali AL-Janabi |
author_sort | Ali AL-Janabi |
collection | DOAJ |
description | Aspergillosis is a common fungal infection with systemic characteristics, which is caused by various species of Aspergillus. The infection could develop in immunocompromised and immunocompetent patients under specific circumstances. Based on the clinical features and type of invasion, aspergillosis could be classified into four main categories, including invasive pulmonary aspergillosis (IPA), noninvasive aspergilloma, semi-invasive chronic pulmonary aspergillosis, and allergic bronchopulmonary aspergillosis (ABPA). Treatment with immunosuppressive drugs for inflammatory diseases, such as rheumatoid arthritis (RA), increases the infection rate with aspergillosis. RA is an autoimmune disease characterized by several chronic symptoms in the joints, including pain, stiffness, and chronic synovitis. Previous studies have denoted an association between RA and aspergillosis. Inhibitory drugs of tumor necrosis factors and steroids are widely used in the treatment of RA. ABPA and IPA are the most commonly diagnosed diseases in patients with RA. The present study aimed to review the effects of RA and its treatment on the development of aspergillosis. |
first_indexed | 2024-04-11T04:46:07Z |
format | Article |
id | doaj.art-ece586949bb040219eaf2ba089733a8d |
institution | Directory Open Access Journal |
issn | 2345-6256 2345-6892 |
language | English |
last_indexed | 2024-04-11T04:46:07Z |
publishDate | 2020-03-01 |
publisher | Mashhad University of Medical Sciences |
record_format | Article |
series | Reviews in Clinical Medicine |
spelling | doaj.art-ece586949bb040219eaf2ba089733a8d2022-12-27T13:05:41ZengMashhad University of Medical SciencesReviews in Clinical Medicine2345-62562345-68922020-03-016415516410.22038/rcm.2020.45709.130215121Therapeutic effects of Rheumatoid Arthritis on Aspergillosis developmentAli AL-Janabi0Department of Microbiology, College of Medicine, University of Karbala, Karbala,Iraq.Aspergillosis is a common fungal infection with systemic characteristics, which is caused by various species of Aspergillus. The infection could develop in immunocompromised and immunocompetent patients under specific circumstances. Based on the clinical features and type of invasion, aspergillosis could be classified into four main categories, including invasive pulmonary aspergillosis (IPA), noninvasive aspergilloma, semi-invasive chronic pulmonary aspergillosis, and allergic bronchopulmonary aspergillosis (ABPA). Treatment with immunosuppressive drugs for inflammatory diseases, such as rheumatoid arthritis (RA), increases the infection rate with aspergillosis. RA is an autoimmune disease characterized by several chronic symptoms in the joints, including pain, stiffness, and chronic synovitis. Previous studies have denoted an association between RA and aspergillosis. Inhibitory drugs of tumor necrosis factors and steroids are widely used in the treatment of RA. ABPA and IPA are the most commonly diagnosed diseases in patients with RA. The present study aimed to review the effects of RA and its treatment on the development of aspergillosis.https://rcm.mums.ac.ir/article_15121_2838ee381264db9cf0abaa51852a3c8a.pdfaspergillomaaspergillosisrheumatoid arthritistnf inhibitors |
spellingShingle | Ali AL-Janabi Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development Reviews in Clinical Medicine aspergilloma aspergillosis rheumatoid arthritis tnf inhibitors |
title | Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development |
title_full | Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development |
title_fullStr | Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development |
title_full_unstemmed | Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development |
title_short | Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development |
title_sort | therapeutic effects of rheumatoid arthritis on aspergillosis development |
topic | aspergilloma aspergillosis rheumatoid arthritis tnf inhibitors |
url | https://rcm.mums.ac.ir/article_15121_2838ee381264db9cf0abaa51852a3c8a.pdf |
work_keys_str_mv | AT alialjanabi therapeuticeffectsofrheumatoidarthritisonaspergillosisdevelopment |