A challenging case of cutaneous leishmaniasis with thrombophlebitic complication

Abstract We report a case of cutaneous leishmaniasis caused by Leishmania guyanensis with sporotrichoid lymphocutaneous dissemination of the parasite and thrombophlebitic complication in a 32‐year‐old man who had recently travelled to French Guiana. After initial failure of empirical treatment with...

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Main Authors: Antoine Willemart, Laura Mengeot, Jean‐Cyr Yombi, Léo Paul Secco, Marie Baeck
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:JEADV Clinical Practice
Subjects:
Online Access:https://doi.org/10.1002/jvc2.244
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author Antoine Willemart
Laura Mengeot
Jean‐Cyr Yombi
Léo Paul Secco
Marie Baeck
author_facet Antoine Willemart
Laura Mengeot
Jean‐Cyr Yombi
Léo Paul Secco
Marie Baeck
author_sort Antoine Willemart
collection DOAJ
description Abstract We report a case of cutaneous leishmaniasis caused by Leishmania guyanensis with sporotrichoid lymphocutaneous dissemination of the parasite and thrombophlebitic complication in a 32‐year‐old man who had recently travelled to French Guiana. After initial failure of empirical treatment with amphotericin B, the patient evolved favourably on high doses of intramuscular injections of meglumine antimoniate for 2 months. This case illustrates the existence of lymphocutaneous forms and possible thrombophlebitic complications of leishmaniasis. It also highlights the challenges in the management of leishmaniasis, despite the existence of guidelines and a wide therapeutic arsenal.
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spelling doaj.art-ece944d0d9a44dac93df1885afab15082023-12-01T10:43:27ZengWileyJEADV Clinical Practice2768-65662023-12-012494795010.1002/jvc2.244A challenging case of cutaneous leishmaniasis with thrombophlebitic complicationAntoine Willemart0Laura Mengeot1Jean‐Cyr Yombi2Léo Paul Secco3Marie Baeck4Department of Dermatology, Cliniques universitaires Saint‐Luc Université catholique de Louvain (UCLouvain) Brussels BelgiumDepartment of Dermatology, Cliniques universitaires Saint‐Luc Université catholique de Louvain (UCLouvain) Brussels BelgiumDepartment of Infectious diseases, Cliniques universitaires Saint‐Luc Université catholique de Louvain (UCLouvain) Brussels BelgiumDepartment of Dermatology, Cliniques universitaires Saint‐Luc Université catholique de Louvain (UCLouvain) Brussels BelgiumDepartment of Dermatology, Cliniques universitaires Saint‐Luc Université catholique de Louvain (UCLouvain) Brussels BelgiumAbstract We report a case of cutaneous leishmaniasis caused by Leishmania guyanensis with sporotrichoid lymphocutaneous dissemination of the parasite and thrombophlebitic complication in a 32‐year‐old man who had recently travelled to French Guiana. After initial failure of empirical treatment with amphotericin B, the patient evolved favourably on high doses of intramuscular injections of meglumine antimoniate for 2 months. This case illustrates the existence of lymphocutaneous forms and possible thrombophlebitic complications of leishmaniasis. It also highlights the challenges in the management of leishmaniasis, despite the existence of guidelines and a wide therapeutic arsenal.https://doi.org/10.1002/jvc2.244L. guyanensisLeishmaniasisliposomal amphotericin Bpentavalent antimonialssporotrichoid disseminationthrombophlebitis
spellingShingle Antoine Willemart
Laura Mengeot
Jean‐Cyr Yombi
Léo Paul Secco
Marie Baeck
A challenging case of cutaneous leishmaniasis with thrombophlebitic complication
JEADV Clinical Practice
L. guyanensis
Leishmaniasis
liposomal amphotericin B
pentavalent antimonials
sporotrichoid dissemination
thrombophlebitis
title A challenging case of cutaneous leishmaniasis with thrombophlebitic complication
title_full A challenging case of cutaneous leishmaniasis with thrombophlebitic complication
title_fullStr A challenging case of cutaneous leishmaniasis with thrombophlebitic complication
title_full_unstemmed A challenging case of cutaneous leishmaniasis with thrombophlebitic complication
title_short A challenging case of cutaneous leishmaniasis with thrombophlebitic complication
title_sort challenging case of cutaneous leishmaniasis with thrombophlebitic complication
topic L. guyanensis
Leishmaniasis
liposomal amphotericin B
pentavalent antimonials
sporotrichoid dissemination
thrombophlebitis
url https://doi.org/10.1002/jvc2.244
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