Using government data to understand the use and availability of medicines for hypertension and diabetes: lessons from Peru

Background Regular measurement of the availability and use of key medicines for non-communicable diseases allows the tracking of progress to achieve equitable access to medicines. Using a country-level public sector monitoring system for medicine supply, we aim to evaluate the availability and use o...

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Main Authors: Janeth Tenorio-Mucha, María Lazo-Porras, Jessica Zafra, Margaret Ewen, David Beran
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Journal of Pharmaceutical Policy and Practice
Subjects:
Online Access:http://dx.doi.org/10.1186/s40545-022-00481-5
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author Janeth Tenorio-Mucha
María Lazo-Porras
Jessica Zafra
Margaret Ewen
David Beran
author_facet Janeth Tenorio-Mucha
María Lazo-Porras
Jessica Zafra
Margaret Ewen
David Beran
author_sort Janeth Tenorio-Mucha
collection DOAJ
description Background Regular measurement of the availability and use of key medicines for non-communicable diseases allows the tracking of progress to achieve equitable access to medicines. Using a country-level public sector monitoring system for medicine supply, we aim to evaluate the availability and use of losartan 50 mg tablets and metformin 850 mg tablets between 2015 and 2020 investigating the impact of different policy changes and the COVID-19 pandemic. Methods Data from the Peruvian National System of Medicine Supply were analyzed using an interrupted time series analysis with known and unknown structural breaks. The outcomes assessed were medicine use (monthly doses dispensed at facilities over time) and medicine availability (proportion of facilities that reported having the medicine available). Results The use of losartan and metformin at the primary level of care had a linear increasing trend over the period of analysis. In secondary and tertiary levels of care, there were no increases but some significant level and trend changes of doses dispensed at different times between 2017 to 2019, but none were related to the change of procurement procedures. At all levels of care, the COVID-19 onset in April 2020 caused an abrupt drop in doses dispensed especially at the primary level. Regarding availability, we found an increasing linear trend in the primary level of care for both medicines. In secondary and tertiary levels of care, the availability fluctuated between 40 and 95%. The onset of the COVID-19 pandemic did not significantly impact medicine availability, except for losartan in the tertiary level of care. Conclusion The availability and proper dispensing of first-line medicines for hypertension and diabetes is an essential factor for sustainable and equitable treatment. Health care systems need to be prepared for forecasting the increasing demand of medicines for chronic diseases, but also to maintain effective medicine supply chains during humanitarian crisis like pandemics.
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spelling doaj.art-ecee57ba07b643a7bfcf4b4e03ab5a1b2023-12-07T15:28:05ZengTaylor & Francis GroupJournal of Pharmaceutical Policy and Practice2052-32112022-12-0115110.1186/s40545-022-00481-512315392Using government data to understand the use and availability of medicines for hypertension and diabetes: lessons from PeruJaneth Tenorio-Mucha0María Lazo-Porras1Jessica Zafra2Margaret Ewen3David Beran4CRONICAS Centre of Excellence in Chronic Diseases,CRONICAS Centre of Excellence in Chronic Diseases,CRONICAS Centre of Excellence in Chronic Diseases,Health Action International,Division of Tropical and Humanitarian Medicine,Background Regular measurement of the availability and use of key medicines for non-communicable diseases allows the tracking of progress to achieve equitable access to medicines. Using a country-level public sector monitoring system for medicine supply, we aim to evaluate the availability and use of losartan 50 mg tablets and metformin 850 mg tablets between 2015 and 2020 investigating the impact of different policy changes and the COVID-19 pandemic. Methods Data from the Peruvian National System of Medicine Supply were analyzed using an interrupted time series analysis with known and unknown structural breaks. The outcomes assessed were medicine use (monthly doses dispensed at facilities over time) and medicine availability (proportion of facilities that reported having the medicine available). Results The use of losartan and metformin at the primary level of care had a linear increasing trend over the period of analysis. In secondary and tertiary levels of care, there were no increases but some significant level and trend changes of doses dispensed at different times between 2017 to 2019, but none were related to the change of procurement procedures. At all levels of care, the COVID-19 onset in April 2020 caused an abrupt drop in doses dispensed especially at the primary level. Regarding availability, we found an increasing linear trend in the primary level of care for both medicines. In secondary and tertiary levels of care, the availability fluctuated between 40 and 95%. The onset of the COVID-19 pandemic did not significantly impact medicine availability, except for losartan in the tertiary level of care. Conclusion The availability and proper dispensing of first-line medicines for hypertension and diabetes is an essential factor for sustainable and equitable treatment. Health care systems need to be prepared for forecasting the increasing demand of medicines for chronic diseases, but also to maintain effective medicine supply chains during humanitarian crisis like pandemics.http://dx.doi.org/10.1186/s40545-022-00481-5essential drugsdrug utilizationlosartanmetforminsegmented regressiontime series
spellingShingle Janeth Tenorio-Mucha
María Lazo-Porras
Jessica Zafra
Margaret Ewen
David Beran
Using government data to understand the use and availability of medicines for hypertension and diabetes: lessons from Peru
Journal of Pharmaceutical Policy and Practice
essential drugs
drug utilization
losartan
metformin
segmented regression
time series
title Using government data to understand the use and availability of medicines for hypertension and diabetes: lessons from Peru
title_full Using government data to understand the use and availability of medicines for hypertension and diabetes: lessons from Peru
title_fullStr Using government data to understand the use and availability of medicines for hypertension and diabetes: lessons from Peru
title_full_unstemmed Using government data to understand the use and availability of medicines for hypertension and diabetes: lessons from Peru
title_short Using government data to understand the use and availability of medicines for hypertension and diabetes: lessons from Peru
title_sort using government data to understand the use and availability of medicines for hypertension and diabetes lessons from peru
topic essential drugs
drug utilization
losartan
metformin
segmented regression
time series
url http://dx.doi.org/10.1186/s40545-022-00481-5
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