Free L-Lysine and Its Methyl Ester React with Glyoxal and Methylglyoxal in Phosphate Buffer (100 mM, pH 7.4) to Form <i>N</i><sup>ε</sup>-Carboxymethyl-Lysine, <i>N</i><sup>ε</sup>-Carboxyethyl-Lysine and <i>N</i><sup>ε</sup>-Hydroxymethyl-Lysine

Free L-Lysine and Its Methyl Ester React with Glyoxal and Methylglyoxal in Phosphate Buffer (100 mM, pH 7.4) to Form <i>N</i><sup>ε</sup>-Carboxymethyl-Lysine, <i>N</i><sup>ε</sup>-Carboxyethyl-Lysine and <i>N</i><sup>ε</sup>-Hydroxymethyl-Lysine

Glyoxal (GO) and methylglyoxal (MGO) are highly reactive species formed in carbohydrate metabolism. <i>N<sup>ε</sup></i>-Carboxymethyllysine (CML) and <i>N</i><sup>ε</sup>-carboxyethyllysine (CEL) are considered to be the advanced glycation end-product...

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Bibliographic Details
Main Authors:	Svetlana Baskal, Dimitrios Tsikas
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Series:	International Journal of Molecular Sciences
Subjects:	AGEs amino acids buffer dicarbonyls disproportionation GC-MS
Online Access:	https://www.mdpi.com/1422-0067/23/7/3446

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