ROK study-C (Rainbow of KIBOU study-colorectum): a colorectal cancer survivor cohort study on food, nutrition, physical activity, psychosocial factors and its influences on colorectal cancer recurrence, survival and quality of life in Japan
Abstract Background Many studies have shown that lifestyle factors such as diet, physical activity are related to the incidence of cancer. However, there are few studies on the association between lifestyle factors and cancer prognosis. To investigate the influence of lifestyle factors and psychosoc...
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| Format: | Article |
| Language: | English |
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BMC
2018-10-01
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| Series: | BMC Cancer |
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| Online Access: | http://link.springer.com/article/10.1186/s12885-018-4830-7 |
| _version_ | 1819264826620248064 |
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| author | Yuri Mizota Yukihide Kanemitsu Shunsuke Tsukamoto Dai Shida Hiroki Ochiai Seiichiro Yamamoto |
| author_facet | Yuri Mizota Yukihide Kanemitsu Shunsuke Tsukamoto Dai Shida Hiroki Ochiai Seiichiro Yamamoto |
| author_sort | Yuri Mizota |
| collection | DOAJ |
| description | Abstract Background Many studies have shown that lifestyle factors such as diet, physical activity are related to the incidence of cancer. However, there are few studies on the association between lifestyle factors and cancer prognosis. To investigate the influence of lifestyle factors and psychosocial factors on prognosis, we started a prospective study of women with breast cancer, the Rainbow of KIBOU study-Breast (ROK Study-B) in 2007. As of February 2018, more than 6300 women have been enrolled, thus making this one of the world’s largest cancer patient cohort studies. Based on the know-how obtained from this study, we started another new cohort study for colorectal cancer patient (ROK Study-C). Methods The ROK Study-C is a prospective observational study for colorectal cancer survivors at the National Cancer Center Hospital. Participants fill in several self-administrated questionnaires about lifestyle, psychosocial factors (including posttraumatic growth and benefit finding, support), and quality of life (QOL) 5 times in total: at diagnosis, 3 and 6 months, 1 and 5 years after surgery. CT-scans will be collected to assess body composition and obesity. We also use blood and cancer tissue from the Biobank. The primary endpoint is disease-free survival. The secondary endpoints are overall survival and health-related QOL. The planned sample size is 2000 and the follow-up period is 5 years after the last enrollment. Discussion Recruitment began in December 2015 and the study is still ongoing. The ROK Study-C will contribute to improvements in patient prognosis and yield important evidence for colorectal cancer survivorship. |
| first_indexed | 2024-12-23T20:35:39Z |
| format | Article |
| id | doaj.art-ecf0b94a351d40c08b83af1d7ced55a0 |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-12-23T20:35:39Z |
| publishDate | 2018-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-ecf0b94a351d40c08b83af1d7ced55a02022-12-21T17:32:06ZengBMCBMC Cancer1471-24072018-10-011811910.1186/s12885-018-4830-7ROK study-C (Rainbow of KIBOU study-colorectum): a colorectal cancer survivor cohort study on food, nutrition, physical activity, psychosocial factors and its influences on colorectal cancer recurrence, survival and quality of life in JapanYuri Mizota0Yukihide Kanemitsu1Shunsuke Tsukamoto2Dai Shida3Hiroki Ochiai4Seiichiro Yamamoto5Division of Health Sociology, Center for Public Health Sciences, National Cancer CenterDepartment of Colorectal Surgery, National Cancer Center HospitalDepartment of Colorectal Surgery, National Cancer Center HospitalDepartment of Colorectal Surgery, National Cancer Center HospitalDepartment of Colorectal Surgery, National Cancer Center HospitalDivision of Health Sociology, Center for Public Health Sciences, National Cancer CenterAbstract Background Many studies have shown that lifestyle factors such as diet, physical activity are related to the incidence of cancer. However, there are few studies on the association between lifestyle factors and cancer prognosis. To investigate the influence of lifestyle factors and psychosocial factors on prognosis, we started a prospective study of women with breast cancer, the Rainbow of KIBOU study-Breast (ROK Study-B) in 2007. As of February 2018, more than 6300 women have been enrolled, thus making this one of the world’s largest cancer patient cohort studies. Based on the know-how obtained from this study, we started another new cohort study for colorectal cancer patient (ROK Study-C). Methods The ROK Study-C is a prospective observational study for colorectal cancer survivors at the National Cancer Center Hospital. Participants fill in several self-administrated questionnaires about lifestyle, psychosocial factors (including posttraumatic growth and benefit finding, support), and quality of life (QOL) 5 times in total: at diagnosis, 3 and 6 months, 1 and 5 years after surgery. CT-scans will be collected to assess body composition and obesity. We also use blood and cancer tissue from the Biobank. The primary endpoint is disease-free survival. The secondary endpoints are overall survival and health-related QOL. The planned sample size is 2000 and the follow-up period is 5 years after the last enrollment. Discussion Recruitment began in December 2015 and the study is still ongoing. The ROK Study-C will contribute to improvements in patient prognosis and yield important evidence for colorectal cancer survivorship.http://link.springer.com/article/10.1186/s12885-018-4830-7Colorectal cancerSurvivorship cohortDietPhysical activityPsychosocial factor |
| spellingShingle | Yuri Mizota Yukihide Kanemitsu Shunsuke Tsukamoto Dai Shida Hiroki Ochiai Seiichiro Yamamoto ROK study-C (Rainbow of KIBOU study-colorectum): a colorectal cancer survivor cohort study on food, nutrition, physical activity, psychosocial factors and its influences on colorectal cancer recurrence, survival and quality of life in Japan BMC Cancer Colorectal cancer Survivorship cohort Diet Physical activity Psychosocial factor |
| title | ROK study-C (Rainbow of KIBOU study-colorectum): a colorectal cancer survivor cohort study on food, nutrition, physical activity, psychosocial factors and its influences on colorectal cancer recurrence, survival and quality of life in Japan |
| title_full | ROK study-C (Rainbow of KIBOU study-colorectum): a colorectal cancer survivor cohort study on food, nutrition, physical activity, psychosocial factors and its influences on colorectal cancer recurrence, survival and quality of life in Japan |
| title_fullStr | ROK study-C (Rainbow of KIBOU study-colorectum): a colorectal cancer survivor cohort study on food, nutrition, physical activity, psychosocial factors and its influences on colorectal cancer recurrence, survival and quality of life in Japan |
| title_full_unstemmed | ROK study-C (Rainbow of KIBOU study-colorectum): a colorectal cancer survivor cohort study on food, nutrition, physical activity, psychosocial factors and its influences on colorectal cancer recurrence, survival and quality of life in Japan |
| title_short | ROK study-C (Rainbow of KIBOU study-colorectum): a colorectal cancer survivor cohort study on food, nutrition, physical activity, psychosocial factors and its influences on colorectal cancer recurrence, survival and quality of life in Japan |
| title_sort | rok study c rainbow of kibou study colorectum a colorectal cancer survivor cohort study on food nutrition physical activity psychosocial factors and its influences on colorectal cancer recurrence survival and quality of life in japan |
| topic | Colorectal cancer Survivorship cohort Diet Physical activity Psychosocial factor |
| url | http://link.springer.com/article/10.1186/s12885-018-4830-7 |
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