Responses of rat bone marrow mesenchymal stem cells to graphene oxide films with different alkali treatment
Graphene oxide (GO) has been widely investigated in biomedical fields due to its excellent biocompatibility. In the present study, GO films were fabricated on titanium surface by cathode electrophoretic deposition with the help of Mg2+ and Al3+. Responses of rat bone marrow mesenchymal stem cells to...
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| Format: | Article |
| Language: | English |
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Elsevier
2019-11-01
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| Series: | Journal of Materials Research and Technology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2238785419310944 |
| _version_ | 1818112878902771712 |
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| author | Lu Liu Jiajun Qiu Xuanyong Liu |
| author_facet | Lu Liu Jiajun Qiu Xuanyong Liu |
| author_sort | Lu Liu |
| collection | DOAJ |
| description | Graphene oxide (GO) has been widely investigated in biomedical fields due to its excellent biocompatibility. In the present study, GO films were fabricated on titanium surface by cathode electrophoretic deposition with the help of Mg2+ and Al3+. Responses of rat bone marrow mesenchymal stem cells to GO films with different alkali treatment, including urea hydrothermal treatment and sodium hydroxide hydrothermal treatment, were investigated. The results indicated that GO films with urea hydrothermal treatment could promote cell proliferation and improve alkaline phosphatase activity. On the contrary, GO films with sodium hydroxide hydrothermal treatment inhibited cell proliferation. Keywords: Biomaterials, Electrodeposition, Alkali treatment, Graphene oxide, Cell proliferation, Titanium |
| first_indexed | 2024-12-11T03:25:56Z |
| format | Article |
| id | doaj.art-ecf59a6035d942e78e3414b9d58aa08a |
| institution | Directory Open Access Journal |
| issn | 2238-7854 |
| language | English |
| last_indexed | 2024-12-11T03:25:56Z |
| publishDate | 2019-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Materials Research and Technology |
| spelling | doaj.art-ecf59a6035d942e78e3414b9d58aa08a2022-12-22T01:22:30ZengElsevierJournal of Materials Research and Technology2238-78542019-11-018653445347Responses of rat bone marrow mesenchymal stem cells to graphene oxide films with different alkali treatmentLu Liu0Jiajun Qiu1Xuanyong Liu2State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China; The Key Laboratory of Resource Chemistry of Ministry of Education, Shanghai Key Laboratory of the Rare Earth Functional Materials, and Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, Shanghai Normal University, Shanghai 200234, ChinaState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing 100049, ChinaState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing 100049, China; Corresponding author at: State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China.Graphene oxide (GO) has been widely investigated in biomedical fields due to its excellent biocompatibility. In the present study, GO films were fabricated on titanium surface by cathode electrophoretic deposition with the help of Mg2+ and Al3+. Responses of rat bone marrow mesenchymal stem cells to GO films with different alkali treatment, including urea hydrothermal treatment and sodium hydroxide hydrothermal treatment, were investigated. The results indicated that GO films with urea hydrothermal treatment could promote cell proliferation and improve alkaline phosphatase activity. On the contrary, GO films with sodium hydroxide hydrothermal treatment inhibited cell proliferation. Keywords: Biomaterials, Electrodeposition, Alkali treatment, Graphene oxide, Cell proliferation, Titaniumhttp://www.sciencedirect.com/science/article/pii/S2238785419310944 |
| spellingShingle | Lu Liu Jiajun Qiu Xuanyong Liu Responses of rat bone marrow mesenchymal stem cells to graphene oxide films with different alkali treatment Journal of Materials Research and Technology |
| title | Responses of rat bone marrow mesenchymal stem cells to graphene oxide films with different alkali treatment |
| title_full | Responses of rat bone marrow mesenchymal stem cells to graphene oxide films with different alkali treatment |
| title_fullStr | Responses of rat bone marrow mesenchymal stem cells to graphene oxide films with different alkali treatment |
| title_full_unstemmed | Responses of rat bone marrow mesenchymal stem cells to graphene oxide films with different alkali treatment |
| title_short | Responses of rat bone marrow mesenchymal stem cells to graphene oxide films with different alkali treatment |
| title_sort | responses of rat bone marrow mesenchymal stem cells to graphene oxide films with different alkali treatment |
| url | http://www.sciencedirect.com/science/article/pii/S2238785419310944 |
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