Gastrointestinal perforation: relation to corticosteroid use and COPD – a case report
Gastrointestinal perforations are a complication of 2–10% of duodenal ulcers. There are a variety of etiologies associated with duodenal ulcer formation and its complications. Corticosteroid use is associated with an increased risk of duodenal ulcer perforation, with the first documented case in 195...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Greater Baltimore Medical Center
2016-09-01
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| Series: | Journal of Community Hospital Internal Medicine Perspectives |
| Subjects: | |
| Online Access: | http://www.jchimp.net/index.php/jchimp/article/view/32129/pdf_202 |
| _version_ | 1828078678697836544 |
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| author | Michael H.K. Nguyen Krista M. Isaac Rebecca Dougherty |
| author_facet | Michael H.K. Nguyen Krista M. Isaac Rebecca Dougherty |
| author_sort | Michael H.K. Nguyen |
| collection | DOAJ |
| description | Gastrointestinal perforations are a complication of 2–10% of duodenal ulcers. There are a variety of etiologies associated with duodenal ulcer formation and its complications. Corticosteroid use is associated with an increased risk of duodenal ulcer perforation, with the first documented case in 1950. Other important medications associated with perforation include NSAIDS and opioids. Beyond medication, one of the most common disease processes, chronic obstructive pulmonary disease (COPD), has been found to be associated with peptic ulcer disease. Up to 30% of COPD patients have been found to have peptic ulcers, and COPD frequency in peptic ulcer disease is 2–3 times the general population. We herein present a case of an acute duodenal ulcer perforation in a patient receiving corticosteroid treatment for an acute COPD exacerbation. |
| first_indexed | 2024-04-11T02:50:19Z |
| format | Article |
| id | doaj.art-ecf995badef543f3b7c8b923c726315a |
| institution | Directory Open Access Journal |
| issn | 2000-9666 |
| language | English |
| last_indexed | 2024-04-11T02:50:19Z |
| publishDate | 2016-09-01 |
| publisher | Greater Baltimore Medical Center |
| record_format | Article |
| series | Journal of Community Hospital Internal Medicine Perspectives |
| spelling | doaj.art-ecf995badef543f3b7c8b923c726315a2023-01-02T16:34:03ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662016-09-01641210.3402/jchimp.v6.3212932129Gastrointestinal perforation: relation to corticosteroid use and COPD – a case reportMichael H.K. Nguyen0Krista M. Isaac1Rebecca Dougherty2 Department of Internal Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA Department of Internal Medicine, Lankenau Medical Center, Philadelphia, PA, USA Department of Internal Medicine, Lankenau Medical Center, Philadelphia, PA, USAGastrointestinal perforations are a complication of 2–10% of duodenal ulcers. There are a variety of etiologies associated with duodenal ulcer formation and its complications. Corticosteroid use is associated with an increased risk of duodenal ulcer perforation, with the first documented case in 1950. Other important medications associated with perforation include NSAIDS and opioids. Beyond medication, one of the most common disease processes, chronic obstructive pulmonary disease (COPD), has been found to be associated with peptic ulcer disease. Up to 30% of COPD patients have been found to have peptic ulcers, and COPD frequency in peptic ulcer disease is 2–3 times the general population. We herein present a case of an acute duodenal ulcer perforation in a patient receiving corticosteroid treatment for an acute COPD exacerbation.http://www.jchimp.net/index.php/jchimp/article/view/32129/pdf_202intestinal perforationsteroidsCOPD exacerbationpeptic ulceracute |
| spellingShingle | Michael H.K. Nguyen Krista M. Isaac Rebecca Dougherty Gastrointestinal perforation: relation to corticosteroid use and COPD – a case report Journal of Community Hospital Internal Medicine Perspectives intestinal perforation steroids COPD exacerbation peptic ulcer acute |
| title | Gastrointestinal perforation: relation to corticosteroid use and COPD – a case report |
| title_full | Gastrointestinal perforation: relation to corticosteroid use and COPD – a case report |
| title_fullStr | Gastrointestinal perforation: relation to corticosteroid use and COPD – a case report |
| title_full_unstemmed | Gastrointestinal perforation: relation to corticosteroid use and COPD – a case report |
| title_short | Gastrointestinal perforation: relation to corticosteroid use and COPD – a case report |
| title_sort | gastrointestinal perforation relation to corticosteroid use and copd a case report |
| topic | intestinal perforation steroids COPD exacerbation peptic ulcer acute |
| url | http://www.jchimp.net/index.php/jchimp/article/view/32129/pdf_202 |
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