THE CORONARY VASCULATURE AND THE MYOCARDIUM
It has been reported that the activity of bradykinin on vascular endothelial receptors results in vasodilatation ( 1-3) due to the release of both nitric oxide (NO) and the so called endothelial-derived hyperpolarizing factor (EDHF) (4-7). It has also been suggested that in the rat bradykinin-induc...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
1999-12-01
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| Series: | Journal of Biological Research |
| Online Access: | https://www.pagepressjournals.org/index.php/jbr/article/view/10856 |
| _version_ | 1798024106573037568 |
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| author | F. Ceresa A. Delfino A. De Matteis N. Ferrero M. Novarino A. Rittà |
| author_facet | F. Ceresa A. Delfino A. De Matteis N. Ferrero M. Novarino A. Rittà |
| author_sort | F. Ceresa |
| collection | DOAJ |
| description |
It has been reported that the activity of bradykinin on vascular endothelial receptors results in vasodilatation ( 1-3) due to the release of both nitric oxide (NO) and the so called endothelial-derived hyperpolarizing factor (EDHF) (4-7). It has also been suggested that in the rat bradykinin-induced vasodilatation is not mediated by NO but by EDHF only (2). Although a number of compounds can cause hyperpolarization of the smooth muscle fibres .of the vascular wall, in the coronary bed of the rat and some other species EDHF has been identified with a non-prostanoid autacoid produced by the activity of cytochrome P-450 on arachidonic acid (3). This autacoid is likely to be one of the epoxiecocystrienoic acids (EETs) (8,9). [...]
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| first_indexed | 2024-04-11T17:57:02Z |
| format | Article |
| id | doaj.art-ecfacd26709d47a9af48f4f6b9402d53 |
| institution | Directory Open Access Journal |
| issn | 1826-8838 2284-0230 |
| language | English |
| last_indexed | 2024-04-11T17:57:02Z |
| publishDate | 1999-12-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Journal of Biological Research |
| spelling | doaj.art-ecfacd26709d47a9af48f4f6b9402d532022-12-22T04:10:43ZengPAGEPress PublicationsJournal of Biological Research1826-88382284-02301999-12-01751-2THE CORONARY VASCULATURE AND THE MYOCARDIUMF. CeresaA. DelfinoA. De MatteisN. FerreroM. NovarinoA. Rittà It has been reported that the activity of bradykinin on vascular endothelial receptors results in vasodilatation ( 1-3) due to the release of both nitric oxide (NO) and the so called endothelial-derived hyperpolarizing factor (EDHF) (4-7). It has also been suggested that in the rat bradykinin-induced vasodilatation is not mediated by NO but by EDHF only (2). Although a number of compounds can cause hyperpolarization of the smooth muscle fibres .of the vascular wall, in the coronary bed of the rat and some other species EDHF has been identified with a non-prostanoid autacoid produced by the activity of cytochrome P-450 on arachidonic acid (3). This autacoid is likely to be one of the epoxiecocystrienoic acids (EETs) (8,9). [...] https://www.pagepressjournals.org/index.php/jbr/article/view/10856 |
| spellingShingle | F. Ceresa A. Delfino A. De Matteis N. Ferrero M. Novarino A. Rittà THE CORONARY VASCULATURE AND THE MYOCARDIUM Journal of Biological Research |
| title | THE CORONARY VASCULATURE AND THE MYOCARDIUM |
| title_full | THE CORONARY VASCULATURE AND THE MYOCARDIUM |
| title_fullStr | THE CORONARY VASCULATURE AND THE MYOCARDIUM |
| title_full_unstemmed | THE CORONARY VASCULATURE AND THE MYOCARDIUM |
| title_short | THE CORONARY VASCULATURE AND THE MYOCARDIUM |
| title_sort | coronary vasculature and the myocardium |
| url | https://www.pagepressjournals.org/index.php/jbr/article/view/10856 |
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