Not COVID-19, Don’t Overlook Pneumocystis in Patients on Gefitinib!
An 82-year-old woman treated for advanced lung cancer with gefitinb was admitted to the emergency unit complaining of dyspnea. Chest computed tomography found abnormalities classified as possible diffuse COVID-19 pneumonia. RT-PCR for Sars-Cov-2 was twice negative. PCR for Pneumocystis jirovecii was...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-02-01
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| Series: | Current Oncology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1718-7729/28/1/94 |
| _version_ | 1797520716598345728 |
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| author | Jérémy Barben Valérie Quipourt Jérémie Vovelle Alain Putot Patrick Manckoundia |
| author_facet | Jérémy Barben Valérie Quipourt Jérémie Vovelle Alain Putot Patrick Manckoundia |
| author_sort | Jérémy Barben |
| collection | DOAJ |
| description | An 82-year-old woman treated for advanced lung cancer with gefitinb was admitted to the emergency unit complaining of dyspnea. Chest computed tomography found abnormalities classified as possible diffuse COVID-19 pneumonia. RT-PCR for Sars-Cov-2 was twice negative. PCR for Pneumocystis jirovecii was positive on bronchoalveolar lavage. The final diagnosis was Pneumocystis jirovecii pneumonia. Therefore, physicians must be careful not to misdiagnose COVID-19, especially in cancer patients on small-molecule therapeutics like gefitinib and corticosteroids. |
| first_indexed | 2024-03-10T08:00:34Z |
| format | Article |
| id | doaj.art-ecfe2cbe47b648e1b35c5c62208209dc |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-10T08:00:34Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-ecfe2cbe47b648e1b35c5c62208209dc2023-11-22T11:31:49ZengMDPI AGCurrent Oncology1198-00521718-77292021-02-0128196196410.3390/curroncol28010094Not COVID-19, Don’t Overlook Pneumocystis in Patients on Gefitinib!Jérémy Barben0Valérie Quipourt1Jérémie Vovelle2Alain Putot3Patrick Manckoundia4Geriatrics Department, University Hospital of Dijon, 21000 Dijon, FranceGeriatrics Department, University Hospital of Dijon, 21000 Dijon, FranceGeriatrics Department, University Hospital of Dijon, 21000 Dijon, FranceGeriatrics Department, University Hospital of Dijon, 21000 Dijon, FranceGeriatrics Department, University Hospital of Dijon, 21000 Dijon, FranceAn 82-year-old woman treated for advanced lung cancer with gefitinb was admitted to the emergency unit complaining of dyspnea. Chest computed tomography found abnormalities classified as possible diffuse COVID-19 pneumonia. RT-PCR for Sars-Cov-2 was twice negative. PCR for Pneumocystis jirovecii was positive on bronchoalveolar lavage. The final diagnosis was Pneumocystis jirovecii pneumonia. Therefore, physicians must be careful not to misdiagnose COVID-19, especially in cancer patients on small-molecule therapeutics like gefitinib and corticosteroids.https://www.mdpi.com/1718-7729/28/1/94COVID-19gefitinibpneumocystis jiroveciityrosine-kinase inhibitor |
| spellingShingle | Jérémy Barben Valérie Quipourt Jérémie Vovelle Alain Putot Patrick Manckoundia Not COVID-19, Don’t Overlook Pneumocystis in Patients on Gefitinib! Current Oncology COVID-19 gefitinib pneumocystis jirovecii tyrosine-kinase inhibitor |
| title | Not COVID-19, Don’t Overlook Pneumocystis in Patients on Gefitinib! |
| title_full | Not COVID-19, Don’t Overlook Pneumocystis in Patients on Gefitinib! |
| title_fullStr | Not COVID-19, Don’t Overlook Pneumocystis in Patients on Gefitinib! |
| title_full_unstemmed | Not COVID-19, Don’t Overlook Pneumocystis in Patients on Gefitinib! |
| title_short | Not COVID-19, Don’t Overlook Pneumocystis in Patients on Gefitinib! |
| title_sort | not covid 19 don t overlook pneumocystis in patients on gefitinib |
| topic | COVID-19 gefitinib pneumocystis jirovecii tyrosine-kinase inhibitor |
| url | https://www.mdpi.com/1718-7729/28/1/94 |
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