Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives

Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives

Influenza viruses represent a major threat to human health and are responsible for seasonal epidemics, along with pandemics. Currently, few therapeutic options are available, with most drugs being at risk of the insurgence of resistant strains. Hence, novel approaches targeting less explored pathway...

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Bibliographic Details
Main Authors: Francesco Fiorentino, Marta De Angelis, Martina Menna, Annarita Rovere, Anna Maria Caccuri, Francesca D’Acunzo, Anna Teresa Palamara, Lucia Nencioni, Dante Rotili, Antonello Mai
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
influenza a virus
nitrobenzoxadiazoles
rna polymerase inhibitors
antivirals
Online Access:http://dx.doi.org/10.1080/14756366.2021.1982932

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