A Case of Prepubertal Ovarian Tissue Cryopreservation in Metachronous Bilateral Mature Ovarian Teratoma Requiring Bilateral Oophorectomy

Mature ovarian teratoma has the potential to occur metachronously in the contralateral ovary. There are significant implications for fertility as bilateral oophorectomy may be indicated. In prepubertal girls, ovarian tissue cryopreservation (OTC) offers the only possibility of a future biological pr...

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Main Authors: Tom Malik, Robert Wheeler, Nigel J. Hall, Juliet Gray
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2022-01-01
Series:European Journal of Pediatric Surgery Reports
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/a-1926-2053
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author Tom Malik
Robert Wheeler
Nigel J. Hall
Juliet Gray
author_facet Tom Malik
Robert Wheeler
Nigel J. Hall
Juliet Gray
author_sort Tom Malik
collection DOAJ
description Mature ovarian teratoma has the potential to occur metachronously in the contralateral ovary. There are significant implications for fertility as bilateral oophorectomy may be indicated. In prepubertal girls, ovarian tissue cryopreservation (OTC) offers the only possibility of a future biological pregnancy but outcome data are limited. We present a case of prepubertal OTC in a 12-year-old girl undergoing a second oophorectomy for metachronous contralateral mature teratoma. We offer a discussion of the challenges that emerged regarding perioperative decision-making, balancing the need for safe oncological resection with the desire to preserve fertility.
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spelling doaj.art-ed0126bed6ac47af82d5d0cbafb2c9e52022-12-22T04:16:04ZengGeorg Thieme Verlag KGEuropean Journal of Pediatric Surgery Reports2194-76192194-76272022-01-011001e148e15110.1055/a-1926-2053A Case of Prepubertal Ovarian Tissue Cryopreservation in Metachronous Bilateral Mature Ovarian Teratoma Requiring Bilateral OophorectomyTom Malik0Robert Wheeler1Nigel J. Hall2Juliet Gray3Department of Paediatric Surgery and Urology, Southampton Children's Hospital, Southampton, United KingdomDepartment of Paediatric Surgery, Southampton Children's Hospital, Southampton, United KingdomFaculty of Medicine, University of Southampton, Southampton, United KingdomCentre for Cancer Immunology, Faculty of Medicine, University of Southampton, Southampton, United KingdomMature ovarian teratoma has the potential to occur metachronously in the contralateral ovary. There are significant implications for fertility as bilateral oophorectomy may be indicated. In prepubertal girls, ovarian tissue cryopreservation (OTC) offers the only possibility of a future biological pregnancy but outcome data are limited. We present a case of prepubertal OTC in a 12-year-old girl undergoing a second oophorectomy for metachronous contralateral mature teratoma. We offer a discussion of the challenges that emerged regarding perioperative decision-making, balancing the need for safe oncological resection with the desire to preserve fertility.http://www.thieme-connect.de/DOI/DOI?10.1055/a-1926-2053mature teratomadermoid cystovarian tumorovarian tissue cryopreservationfertility
spellingShingle Tom Malik
Robert Wheeler
Nigel J. Hall
Juliet Gray
A Case of Prepubertal Ovarian Tissue Cryopreservation in Metachronous Bilateral Mature Ovarian Teratoma Requiring Bilateral Oophorectomy
European Journal of Pediatric Surgery Reports
mature teratoma
dermoid cyst
ovarian tumor
ovarian tissue cryopreservation
fertility
title A Case of Prepubertal Ovarian Tissue Cryopreservation in Metachronous Bilateral Mature Ovarian Teratoma Requiring Bilateral Oophorectomy
title_full A Case of Prepubertal Ovarian Tissue Cryopreservation in Metachronous Bilateral Mature Ovarian Teratoma Requiring Bilateral Oophorectomy
title_fullStr A Case of Prepubertal Ovarian Tissue Cryopreservation in Metachronous Bilateral Mature Ovarian Teratoma Requiring Bilateral Oophorectomy
title_full_unstemmed A Case of Prepubertal Ovarian Tissue Cryopreservation in Metachronous Bilateral Mature Ovarian Teratoma Requiring Bilateral Oophorectomy
title_short A Case of Prepubertal Ovarian Tissue Cryopreservation in Metachronous Bilateral Mature Ovarian Teratoma Requiring Bilateral Oophorectomy
title_sort case of prepubertal ovarian tissue cryopreservation in metachronous bilateral mature ovarian teratoma requiring bilateral oophorectomy
topic mature teratoma
dermoid cyst
ovarian tumor
ovarian tissue cryopreservation
fertility
url http://www.thieme-connect.de/DOI/DOI?10.1055/a-1926-2053
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