Connexin32 gap junction channels deliver miR155-3p to mediate pyroptosis in renal ischemia-reperfusion injury

Connexin32 gap junction channels deliver miR155-3p to mediate pyroptosis in renal ischemia-reperfusion injury

Abstract Objectives To explore whether the gap junction (GJ) composed by connexin32(Cx32) mediated pyroptosis in renal ischemia-reperfusion(I/R) injury via transmitting miR155-3p, with aim to provide new strategies for the prevention and treatment of acute kidney injury (AKI) after renal I/R. Method...

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Bibliographic Details
Main Authors: Liubing Chen, Hongyi Fang, Xiaoyun Li, Peiling Yu, Yu Guan, Cuicui Xiao, Zhizhao Deng, Ziqing Hei, Chaojin Chen, Chenfang Luo
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cell Communication and Signaling
Subjects:
Renal ischemia reperfusion injury
Hypoxia and reoxygenation injury
Connexin32
Pyroptosis
miR155-3p
Online Access:https://doi.org/10.1186/s12964-023-01443-3

Internet

https://doi.org/10.1186/s12964-023-01443-3

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