Characterizing tertiary lymphoid structures associated single-cell atlas in breast cancer patients

Abstract The tertiary lymphoid structure (TLS) is recognized as a potential prognosis factor for breast cancer and is strongly associated with response to immunotherapy. Inducing TLS neogenesis can enhance the immunogenicity of tumors and improve the efficacy of immunotherapy. However, our understan...

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Bibliographic Details
Main Authors: Xiaokai Fan, Daqin Feng, Donggui Wei, Anqi Li, Fangyi Wei, Shufang Deng, Muling Shen, Congzhi Qin, Yongjia Yu, Lun Liang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-025-03635-y