Engineering of small-molecule lipidic prodrugs as novel nanomedicines for enhanced drug delivery

Engineering of small-molecule lipidic prodrugs as novel nanomedicines for enhanced drug delivery

Abstract A widely established prodrug strategy can effectively optimize the unappealing properties of therapeutic agents in cancer treatment. Among them, lipidic prodrugs extremely uplift the physicochemical properties, site-specificity, and antitumor activities of therapeutic agents while reducing...

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Bibliographic Details
Main Authors: Lingling Huang, Jianmiao Yang, Tiantian Wang, Jianqing Gao, Donghang Xu
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Journal of Nanobiotechnology
Subjects:
Cancer
Small molecule
Lipidic prodrug
Nanomedicine
Drug delivery
Online Access:https://doi.org/10.1186/s12951-022-01257-4

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