Long-term outcome of endoprosthetic replacement for proximal femur giant cell tumor
Introduction: Giant cell tumor (GCT) of bone is locally aggressive benign tumor involving the epiphysis of long bones in young adults. Various treatment options include intralesional curettage, extended curettage, wide resection, resection and reconstruction and amputation. The main variables to be...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Nigerian Journal of Surgery |
| Subjects: | |
| Online Access: | http://www.nigerianjsurg.com/article.asp?issn=1117-6806;year=2015;volume=21;issue=2;spage=143;epage=145;aulast=Gosal |
| _version_ | 1819229158280003584 |
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| author | Gurinder Singh Gosal Avneet Boparai Gurpreet Singh Makkar |
| author_facet | Gurinder Singh Gosal Avneet Boparai Gurpreet Singh Makkar |
| author_sort | Gurinder Singh Gosal |
| collection | DOAJ |
| description | Introduction: Giant cell tumor (GCT) of bone is locally aggressive benign tumor involving the epiphysis of long bones in young adults. Various treatment options include intralesional curettage, extended curettage, wide resection, resection and reconstruction and amputation. The main variables to be considered for planning treatment include the site of involvement and Campanacci stage of the tumor. Functional and oncological outcomes of these treatment options vary widely, the predominant detrimental factor being tumor recurrence rate. Aim: A study was conducted to evaluate the long-term oncological and functional outcome of patients with GCT of the proximal femur that underwent tumor resection and endoprosthetic replacement. Materials and Methods: Eleven patients with Campanacci stage-III GCT of proximal femur who underwent wide excision of tumor and endoprosthesis replacement with a mean follow-up the duration of 10.6 years were assessed using standard proforma. The treatment outcome was evaluated using the Revised Musculoskeletal Tumor Society Rating Scale for the lower extremity. Results: At mean follow-up the duration of 10.6 years, none of the cases had tumor recurrence, infection, prosthesis loosening or dislocation. All the patients were community ambulators among whom eight patients were walking without support while three patients were using a cane for support. The mean total Musculoskeletal Tumor Society Score was 26.8 out of 30 indicating the good outcome. Conclusions: The authors recommend that wide resection and endoprosthetic replacement should be considered as a preferred treatment option for proximal femur GCT as the functional, and oncological outcome is satisfactory with this modality of treatment. |
| first_indexed | 2024-12-23T11:08:43Z |
| format | Article |
| id | doaj.art-ed0906530e6b4bb4a04e1e7adf70d437 |
| institution | Directory Open Access Journal |
| issn | 1117-6806 2278-7100 |
| language | English |
| last_indexed | 2024-12-23T11:08:43Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Nigerian Journal of Surgery |
| spelling | doaj.art-ed0906530e6b4bb4a04e1e7adf70d4372022-12-21T17:49:24ZengWolters Kluwer Medknow PublicationsNigerian Journal of Surgery1117-68062278-71002015-01-0121214314510.4103/1117-6806.162583Long-term outcome of endoprosthetic replacement for proximal femur giant cell tumorGurinder Singh GosalAvneet BoparaiGurpreet Singh MakkarIntroduction: Giant cell tumor (GCT) of bone is locally aggressive benign tumor involving the epiphysis of long bones in young adults. Various treatment options include intralesional curettage, extended curettage, wide resection, resection and reconstruction and amputation. The main variables to be considered for planning treatment include the site of involvement and Campanacci stage of the tumor. Functional and oncological outcomes of these treatment options vary widely, the predominant detrimental factor being tumor recurrence rate. Aim: A study was conducted to evaluate the long-term oncological and functional outcome of patients with GCT of the proximal femur that underwent tumor resection and endoprosthetic replacement. Materials and Methods: Eleven patients with Campanacci stage-III GCT of proximal femur who underwent wide excision of tumor and endoprosthesis replacement with a mean follow-up the duration of 10.6 years were assessed using standard proforma. The treatment outcome was evaluated using the Revised Musculoskeletal Tumor Society Rating Scale for the lower extremity. Results: At mean follow-up the duration of 10.6 years, none of the cases had tumor recurrence, infection, prosthesis loosening or dislocation. All the patients were community ambulators among whom eight patients were walking without support while three patients were using a cane for support. The mean total Musculoskeletal Tumor Society Score was 26.8 out of 30 indicating the good outcome. Conclusions: The authors recommend that wide resection and endoprosthetic replacement should be considered as a preferred treatment option for proximal femur GCT as the functional, and oncological outcome is satisfactory with this modality of treatment.http://www.nigerianjsurg.com/article.asp?issn=1117-6806;year=2015;volume=21;issue=2;spage=143;epage=145;aulast=GosalEndoprosthesis megaprosthesisgiant cell tumor of boneproximal femur |
| spellingShingle | Gurinder Singh Gosal Avneet Boparai Gurpreet Singh Makkar Long-term outcome of endoprosthetic replacement for proximal femur giant cell tumor Nigerian Journal of Surgery Endoprosthesis megaprosthesis giant cell tumor of bone proximal femur |
| title | Long-term outcome of endoprosthetic replacement for proximal femur giant cell tumor |
| title_full | Long-term outcome of endoprosthetic replacement for proximal femur giant cell tumor |
| title_fullStr | Long-term outcome of endoprosthetic replacement for proximal femur giant cell tumor |
| title_full_unstemmed | Long-term outcome of endoprosthetic replacement for proximal femur giant cell tumor |
| title_short | Long-term outcome of endoprosthetic replacement for proximal femur giant cell tumor |
| title_sort | long term outcome of endoprosthetic replacement for proximal femur giant cell tumor |
| topic | Endoprosthesis megaprosthesis giant cell tumor of bone proximal femur |
| url | http://www.nigerianjsurg.com/article.asp?issn=1117-6806;year=2015;volume=21;issue=2;spage=143;epage=145;aulast=Gosal |
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