SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens
The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented challenge to our healthcare system. Secondary and concurrent bacterial and viral co-infections are well documented for other viral respira...
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Format: | Article |
Language: | English |
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Elsevier
2021-04-01
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Series: | International Journal of Infectious Diseases |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971221001739 |
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author | Vijay Singh Pallavi Upadhyay Jairus Reddy John Granger |
author_facet | Vijay Singh Pallavi Upadhyay Jairus Reddy John Granger |
author_sort | Vijay Singh |
collection | DOAJ |
description | The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented challenge to our healthcare system. Secondary and concurrent bacterial and viral co-infections are well documented for other viral respiratory pathogens; however knowledge regarding co-infections in COVID-19 remains limited. In the present study, concurrent testing of 50 419 individual samples for the presence of SARS-CoV-2 and other bacterial and viral respiratory pathogens was performed between March and August 2020. Overall, a lower rate of viral co-infection was observed in the SARS-CoV-2-positive population when compared to the population testing negative for the virus. Significant levels of Staphylococcus aureus and Epstein–Barr virus co-infections were detected in the SARS-CoV-2-positive population. This is one of the largest surveys looking into the co-infection patterns of SARS-CoV-2 infection in the United States. Data from this study will enhance our understanding of the current pandemic and will assist clinicians in making better patient care decisions, especially with respect to antimicrobial therapy. |
first_indexed | 2024-12-20T15:03:56Z |
format | Article |
id | doaj.art-ed0982df052448dab9f37dbaaeabe866 |
institution | Directory Open Access Journal |
issn | 1201-9712 |
language | English |
last_indexed | 2024-12-20T15:03:56Z |
publishDate | 2021-04-01 |
publisher | Elsevier |
record_format | Article |
series | International Journal of Infectious Diseases |
spelling | doaj.art-ed0982df052448dab9f37dbaaeabe8662022-12-21T19:36:35ZengElsevierInternational Journal of Infectious Diseases1201-97122021-04-01105617620SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogensVijay Singh0Pallavi Upadhyay1Jairus Reddy2John Granger3Corresponding author.; Department of Molecular Diagnostics, HealthTrackRX, Denton, TX 76207, USADepartment of Molecular Diagnostics, HealthTrackRX, Denton, TX 76207, USADepartment of Molecular Diagnostics, HealthTrackRX, Denton, TX 76207, USADepartment of Molecular Diagnostics, HealthTrackRX, Denton, TX 76207, USAThe global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented challenge to our healthcare system. Secondary and concurrent bacterial and viral co-infections are well documented for other viral respiratory pathogens; however knowledge regarding co-infections in COVID-19 remains limited. In the present study, concurrent testing of 50 419 individual samples for the presence of SARS-CoV-2 and other bacterial and viral respiratory pathogens was performed between March and August 2020. Overall, a lower rate of viral co-infection was observed in the SARS-CoV-2-positive population when compared to the population testing negative for the virus. Significant levels of Staphylococcus aureus and Epstein–Barr virus co-infections were detected in the SARS-CoV-2-positive population. This is one of the largest surveys looking into the co-infection patterns of SARS-CoV-2 infection in the United States. Data from this study will enhance our understanding of the current pandemic and will assist clinicians in making better patient care decisions, especially with respect to antimicrobial therapy.http://www.sciencedirect.com/science/article/pii/S1201971221001739COVID-19Co-infectionsPandemicSARS-CoV-2Respiratory co-infections |
spellingShingle | Vijay Singh Pallavi Upadhyay Jairus Reddy John Granger SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens International Journal of Infectious Diseases COVID-19 Co-infections Pandemic SARS-CoV-2 Respiratory co-infections |
title | SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens |
title_full | SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens |
title_fullStr | SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens |
title_full_unstemmed | SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens |
title_short | SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens |
title_sort | sars cov 2 respiratory co infections incidence of viral and bacterial co pathogens |
topic | COVID-19 Co-infections Pandemic SARS-CoV-2 Respiratory co-infections |
url | http://www.sciencedirect.com/science/article/pii/S1201971221001739 |
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