SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens

The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented challenge to our healthcare system. Secondary and concurrent bacterial and viral co-infections are well documented for other viral respira...

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Main Authors: Vijay Singh, Pallavi Upadhyay, Jairus Reddy, John Granger
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:International Journal of Infectious Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971221001739
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author Vijay Singh
Pallavi Upadhyay
Jairus Reddy
John Granger
author_facet Vijay Singh
Pallavi Upadhyay
Jairus Reddy
John Granger
author_sort Vijay Singh
collection DOAJ
description The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented challenge to our healthcare system. Secondary and concurrent bacterial and viral co-infections are well documented for other viral respiratory pathogens; however knowledge regarding co-infections in COVID-19 remains limited. In the present study, concurrent testing of 50 419 individual samples for the presence of SARS-CoV-2 and other bacterial and viral respiratory pathogens was performed between March and August 2020. Overall, a lower rate of viral co-infection was observed in the SARS-CoV-2-positive population when compared to the population testing negative for the virus. Significant levels of Staphylococcus aureus and Epstein–Barr virus co-infections were detected in the SARS-CoV-2-positive population. This is one of the largest surveys looking into the co-infection patterns of SARS-CoV-2 infection in the United States. Data from this study will enhance our understanding of the current pandemic and will assist clinicians in making better patient care decisions, especially with respect to antimicrobial therapy.
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spelling doaj.art-ed0982df052448dab9f37dbaaeabe8662022-12-21T19:36:35ZengElsevierInternational Journal of Infectious Diseases1201-97122021-04-01105617620SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogensVijay Singh0Pallavi Upadhyay1Jairus Reddy2John Granger3Corresponding author.; Department of Molecular Diagnostics, HealthTrackRX, Denton, TX 76207, USADepartment of Molecular Diagnostics, HealthTrackRX, Denton, TX 76207, USADepartment of Molecular Diagnostics, HealthTrackRX, Denton, TX 76207, USADepartment of Molecular Diagnostics, HealthTrackRX, Denton, TX 76207, USAThe global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented challenge to our healthcare system. Secondary and concurrent bacterial and viral co-infections are well documented for other viral respiratory pathogens; however knowledge regarding co-infections in COVID-19 remains limited. In the present study, concurrent testing of 50 419 individual samples for the presence of SARS-CoV-2 and other bacterial and viral respiratory pathogens was performed between March and August 2020. Overall, a lower rate of viral co-infection was observed in the SARS-CoV-2-positive population when compared to the population testing negative for the virus. Significant levels of Staphylococcus aureus and Epstein–Barr virus co-infections were detected in the SARS-CoV-2-positive population. This is one of the largest surveys looking into the co-infection patterns of SARS-CoV-2 infection in the United States. Data from this study will enhance our understanding of the current pandemic and will assist clinicians in making better patient care decisions, especially with respect to antimicrobial therapy.http://www.sciencedirect.com/science/article/pii/S1201971221001739COVID-19Co-infectionsPandemicSARS-CoV-2Respiratory co-infections
spellingShingle Vijay Singh
Pallavi Upadhyay
Jairus Reddy
John Granger
SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens
International Journal of Infectious Diseases
COVID-19
Co-infections
Pandemic
SARS-CoV-2
Respiratory co-infections
title SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens
title_full SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens
title_fullStr SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens
title_full_unstemmed SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens
title_short SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens
title_sort sars cov 2 respiratory co infections incidence of viral and bacterial co pathogens
topic COVID-19
Co-infections
Pandemic
SARS-CoV-2
Respiratory co-infections
url http://www.sciencedirect.com/science/article/pii/S1201971221001739
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AT pallaviupadhyay sarscov2respiratorycoinfectionsincidenceofviralandbacterialcopathogens
AT jairusreddy sarscov2respiratorycoinfectionsincidenceofviralandbacterialcopathogens
AT johngranger sarscov2respiratorycoinfectionsincidenceofviralandbacterialcopathogens